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Pax9tm1.1(cre)Sbam - Skeletal System
Recombinase Activity Detail
Allele Information
Allele:
Pax9tm1.1(cre)Sbam
paired box 9; targeted mutation 1.1, Simon Bamforth 		Driver: Pax9
Type: Targeted (Null/knockout, Recombinase)
Synonym: Pax9Cre
Molecular description: The targeting construct was designed to replace a 1.06 kb section of the mouse Pax9 gene, spanning the second half of exon two, containing the start codon, and the first half of the 3rd exon, containing the paired box and octapeptide motif, with a promoterless Cre recombinase gene preceded by a consensus Kozak sequence and the FRT-flanked PGK-Neomycin cassette. After homologous recombination in ES cells, the FRT-flanked PGK-neomycin cassette was removed by crossing the derived mice with FLPe mice.
Find mice (IMSR): Mouse Strains: 2 strains available       Cell Lines: 0 lines available
Additional Tissues: Pax9tm1.1(cre)Sbam activity also observed in:
branchial arches, embryo-other, head, mesenchyme, sensory organs
Tissue Information
Skeletal System Other recombinase alleles with activity in Skeletal System tissues:
Images
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J:284143 Fig. 7
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 3 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory