Avpr1b<tm2.1(cre)Wsy> - Head Recombinase Activity Detail MGI Mouse

Avpr1b^{tm2.1(cre)Wsy} - Head
Recombinase Activity Detail

Allele Information | Tissue Information | Images | Recombinase Activity | References

Allele Information

Allele:

Avpr1b^{tm2.1(cre)Wsy}
arginine vasopressin receptor 1B; targeted mutation 2.1, W Scott Young III

Driver: Avpr1b
Type: Targeted (Null/knockout, Recombinase)

Synonym:

Avpr1b-Cre

Molecular description:

The Cre-nuclear localization sequence and FRT flanked pgk-neo cassette was inserted to replace the coding region from the initiating codon in exon 1 of the mouse Avpr1b gene by homologous recombination in the ES cells. The chimeras generated from correctly targetted ES cells were crossed to the FLPe deleter to remove the pgk-neo cassette. The absence of Avpr1b mRNA in brain of homozygous mice was confirmed.

Find mice (IMSR):

Mouse Strains: 1 strain available Cell Lines: 0 lines available

Additional Tissues:

Avpr1b^{tm2.1(cre)Wsy} activity also observed in:
nervous system

Tissue Information

Head

Other recombinase alleles with activity in Head tissues:

7630403G23Rik^{Tg(Th-cre)1Tmd}, Abcg2^{tm1.1(cre/Esr1*)Jvbe}, Acan^{tm1(cre/ERT2)Crm}, Acsm4^tm1(cre)Hsak ...(more)

Images

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J:310526 Fig. 1

J:310526 Fig. 2

J:310526 Fig. 3

Recombinase Activity

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Assays Genotypic Background Result Notes

References

All for this allele:

2 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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