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Allele Information
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Allele:
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Oxttm1.1(icre)Ksak
oxytocin;
targeted mutation 1.1, Kenji Sakimura
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Driver: Oxt
Type: Targeted
(Recombinase)
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Synonym:
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Oxtcre, Oxttm1.1(Cre)Ksak
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Molecular description:
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The sequence of the self-processing furin-2A in front of the improved Cre (iCre) recombinase was inserted into the end of the coding sequence of the mouse Oxt gene. Frt flanked neo cassette was removed by crossing with the Actb-FLPe mouse line that expresses a Flp1 recombinase gene under the human ACTB promoter.
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Find mice (IMSR):
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Mouse Strains:
1
strain available
Cell Lines:
0 lines available
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Additional Tissues:
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Oxttm1.1(icre)Ksak activity also observed in:
head,
nervous system
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Tissue Information
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Endocrine System
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Other recombinase alleles with activity in Endocrine System tissues:
7630403G23RikTg(Th-cre)1Tmd,
Agrptm1(cre)Lowl,
Alpltm1(cre)Nagy,
Ccktm1.1(cre)Zjh,
Cfap126tm1.1(icre)Heli,
Commd10Tg(Vav1-icre)A2Kio,
Cpa1tm1(cre/ERT2)Dam,
Crhtm1.1(flpo)Bsab,
Crhtm1(cre)Zjh,
Cx3cr1tm1.1(cre)Jung,
Cx3cr1tm2.1(cre/ERT2)Jung,
Cyp11a1tm1(GFP/cre)Pzg,
E2f1Tg(Wnt1-cre)2Sor,
Fgf16tm1.1(cre)Sms,
Foxd1tm1(GFP/cre)Amc,
Foxl2tm1(GFP/cre/ERT2)Pzg,
Gad2tm2(cre)Zjh,
Gcgem1(cre)Utr,
Gcgtm1.1(cre/ERT2)Yasu,
Ghem1(cre)Jmz,
Ghsrtm1.1(cre)Jmz,
Glp1rtm1.1(cre)Cors,
Gnao1tm2(EGFP/cre/ERT2)Wtsi,
Golm1tm2(EGFP/cre/ERT2)Wtsi,
Gper1em1(cre)Smoc,
Gt(ROSA)26Sortm1.1(CAG-cre)Jphe,
Gt(ROSA)26Sortm1(cre/ERT2)Tyj,
Gt(ROSA)26Sortm2(icre/ERT2)Jphe,
H2az2Tg(Wnt1-cre)11Rth,
Hand2em1(dre)Pjen,
Hprt1tm1(CAG-cre)Mnn,
Hprt1tm1(TG-cre)1Sasr,
Hprt1tm364a(CAG-icre/ERT2)Ems,
Ifi208Tg(Cspg4-cre)1Akik,
Ihhem1(Tomm20/mKate2,dre)Xya,
Ins1tm1.1(cre)Thor,
Ins1tm2.1(cre/ERT2)Thor,
Krt17tm1(cre)Murr,
Krt19tm1(cre/ERT)Ggu,
Leprtm2(cre)Rck,
Lyve1tm1.1(EGFP/cre)Cys,
Mnx1tm4(cre)Tmj,
Myf5tm3(cre)Sor,
Ndor1Tg(UBC-cre/ERT2)1Ejb,
Nkx2-1tm1.1(cre/ERT2)Zjh,
Nkx2-2tm4.1(cre/EGFP)Suss,
Nkx2-5tm2(cre)Rph,
Notch1tm3(cre)Rko,
Npvftm1.1(icre)Gand,
Nxph4em1(cre)Zak,
Omptm4(cre)Mom,
Oprk1tm1.1(cre)Sros,
Osr2tm2(cre)Jian,
Pax3tm1(cre)Joe,
Pax7tm2.1(cre/ERT2)Fan,
Pbx3tm1(EGFP/cre/ERT2)Wtsi,
Pdx1tm1.1(dre)Gkg,
Pdyntm1.1(cre)Mjkr,
Plxnd1tm2(EGFP/cre/ERT2)Wtsi,
Prlrtm1.1(cre)Uboe,
Ptf1atm1.1(cre)Cvw,
Ptf1atm1(flpo)Hcrd,
Raxtm1.1(cre/ERT2)Sbls,
Rxfp1em1(cre)Ngai,
Setd4em1(cre)Wjy,
Setd4tm2.1(cre/ERT2)Wjy,
Sfta3tm1.1(cre/ERT2)Eem,
Shhtm1(EGFP/cre)Cjt,
Shhtm2(cre/ERT2)Cjt,
Slc17a6tm2(cre)Lowl,
Slc26a9em1(cre)Sms,
Sox2tm1.1(cre/ERT2)Jpmb,
Spink1tm3(cre)Kymm,
Sptbtm2(EGFP/cre/ERT2)Wtsi,
Ssttm2.1(cre)Zjh,
Taglntm2(cre)Yec,
Tbx3em1(cre)Mhts,
Tg(ACTA1-cre)79Jme,
Tg(ACTB-cre)1Tes,
Tg(ACTFLPe)9205Dym,
Tg(Actl6b-cre)4092Jiwu,
Tg(Adipoq-cre)1Evdr,
Tg(Akr1b7-cre)1Anm,
Tg(Alb1-cre)1Dlr,
Tg(Amh-cre)8815Reb,
Tg(Amy2-cre)1Herr,
Tg(CA2-cre)1Subw,
Tg(CA2-cre/Esr1*)1Subw,
Tg(CAG-cre/Esr1*)1Lbe,
Tg(CAG-cre/Esr1*)5Amc,
Tg(Camk2a-cre)1Nobs,
Tg(Camk2a-cre/ERT2)1Aibs,
Tg(Cdh16-cre)91Igr,
Tg(Cdh5-cre)7Mlia,
Tg(CDX2-cre)101Erf,
Tg(Cga-cre)3Sac,
Tg(Cga-icre)961Sac,
Tg(CMV-cre)1Cgn,
Tg(Crx-cre)1Tfur,
Tg(Cryaa-cre)10Mlr,
Tg(Ctgf-cre)2Aibs,
Tg(Cyp11a1-cre)16Mchu,
Tg(Cyp17a1-icre)AJako,
Tg(Cyp1a1-cre)1Dwi,
Tg(Cyp39a1-cre)1Aibs,
Tg(DBH-cre)6-8Koba,
Tg(DBH-cre)9-9Koba,
Tg(Dbh-cre/ERT2)198.1Hroh,
Tg(Ddx4-cre)1Dcas,
Tg(EIIa-cre)C5379Lmgd,
Tg(Eno2-cre)39Jme,
Tg(Fabp4-cre)1Rev,
Tg(Fev-cre)FF9Pasq,
Tg(Gcg-cre)1Herr,
Tg(Gcg-cre)1Slib,
Tg(Gcg-icre)23Cshi,
Tg(GFAP-cre)25Mes,
Tg(Gfap-cre)73.12Mvs,
Tg(Gfap-cre)77.6Mvs,
Tg(GH1-cre)1Sac,
Tg(Gh1-cre)bKnmn,
Tg(Ghrhr-cre)3242Lsk,
Tg(Ghrl-cre)E7Jmz,
Tg(Ghrl-icre)#Weiz,
Tg(Glp1r-icre)#Fmgb,
Tg(Grik4-cre)G32-4Stl,
Tg(Hoxb7-cre)13Amc,
Tg(Hspa2-cre)1Eddy,
Tg(Inha-cre)1Zuk,
Tg(Inha-cre)2Zuk,
Tg(Inha-cre)3Zuk,
Tg(Ins1-cre)25Utr,
Tg(Ins1-cre,-DsRed*T3)#Caoy,
Tg(Ins1-cre/ERT)1Lphi,
Tg(Ins1-cre/ERT2)#Pesch,
Tg(Ins2-cre)23Herr,
Tg(Ins2-cre)25Mgn,
Tg(Ins2-cre/ERT)1Dam,
Tg(Ins2-tTA,tetO-cre)1Ctlh,
Tg(INS-icre)18Msdr,
Tg(Itgax-cre)1-1Reiz,
Tg(Lck-icre)3779Nik,
Tg(Lhb-cre)1Sac,
Tg(LHX3-cre)#Sjr,
Tg(Mbp-cre)6Gvn,
Tg(Mbp-cre)9Gvn,
Tg(Mchr1-cre/ERT2)3Nbe,
Tg(MMTV-cre)4Mam,
Tg(Mx1-cre)1Cgn,
Tg(Nes-cre)1Kln,
Tg(Neurod1-cre)1Able,
Tg(Neurog3-cre)1Dam,
Tg(NEUROG3-cre)1Herr,
Tg(Neurog3-cre)C1Able,
Tg(Neurog3-cre/ERT2)1Able,
Tg(Neurog3-cre/Esr1*)1Dam,
Tg(Nkx2-1-cre)2Sand,
Tg(NPHS2-cre)295Lbh,
Tg(Nr5a1-cre)1Kmor,
Tg(Nr5a1-cre)2Klp,
Tg(Nr5a1-cre)2Lowl,
Tg(Nr5a1-cre)7Lowl,
Tg(Nr5a1-cre/ERT2)4Kmor,
Tg(Pax4-cre)1Dam,
Tg(Pax6-cre)1Rilm,
Tg(Pax6-cre,GFP)1Pgr,
Tg(Pcp2-cre)2Mpin,
Tg(Pdx1-cre)1Herr,
Tg(Pdx1-cre)6Cvw,
Tg(Pdx1-cre)89.1Dam,
Tg(Pdx1-cre/Esr1*)1Mga,
Tg(Pdx1-cre/Esr1*)35.10Dam,
Tg(Pdx1-cre/Esr1*)35.6Dam,
Tg(Pdx1-cre/Esr1*)#Dam,
Tg(Pf4-icre)Q3Rsko,
Tg(Pitx1-cre)7Rsd,
Tg(Pomc1-cre)16Lowl,
Tg(Pomc-cre)5Brn,
Tg(Pomc*-cre/ERT2)#Rlb,
Tg(Pomc*-cre)#Jdr,
Tg(Pomc-dre)#Jcbr,
Tg(Prdm1-cre)1Masu,
Tg(Prl-cre)#Salr,
Tg(Prm-cre)58Og,
Tg(Prop1-cre)1Rsd,
Tg(Prop1-icre)517Sac,
Tg(Prrx1-cre)1Cjt,
Tg(PTH-cre)4167Slib,
Tg(Rarb-cre)1Bhr,
Tg(Relb-cre)53Rie,
Tg(REN-cre)1Haca,
Tg(Ren-cre)#Kwg,
Tg(Scnn1a-cre)3Aibs,
Tg(Sim1-cre)1Lowl,
Tg(Stra8-icre)1Reb,
Tg(Sycp1-cre)4Min,
Tg(Tagln-cre)1Her,
Tg(Tek-cre)1Ywa,
Tg(tetO-cre)1Jaw,
Tg(Tg-cre)1Soff,
Tg(Tg-cre/ERT2)1Kero,
Tg(Th-cre)12Mrub,
Tg(Thy1-cre)1Vln,
Tg(TPO-cre)1Shk,
Tg(Tshb-cre)4Sac,
Tg(Tyr-cre)1Gfk,
Tg(Tyr-cre/ERT2)13Bos,
Tg(Ucp1-cre)1Evdr,
Tg(Vav1-cre)8Cgp,
Tg(Vil1-cre)997Gum,
Tg(Wfs1-cre/ERT2)3Aibs,
Thtm1(cre)Te,
Tmprss2tm1.1(cre/ERT2)Ychen,
Twist2tm1.1(cre)Dor,
Viptm1(cre)Zjh,
Wt1tm1(EGFP/cre)Wtp
(less)
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Images
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J:310161
Fig. 5
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Recombinase Activity
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Assays
Genotypic Background
Result Notes
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References
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