Igs2<tm2(Smarcd3-cre/ERT2)Bbr> - Head Recombinase Activity Detail MGI Mouse

Igs2^{tm2(Smarcd3-cre/ERT2)Bbr} - Head
Recombinase Activity Detail

Allele Information | Images | Recombinase Activity | References

Allele Information

Allele:

Igs2^{tm2(Smarcd3-cre/ERT2)Bbr}
intergenic site 2; targeted mutation 2, Benoit G Bruneau

Driver: Smarcd3
Type: Targeted (Inducible, Recombinase)

Inducer:

tamoxifen

Synonym:

F6CreERT2, Smarcd3-F6CreERT2

Molecular description:

Site-specific PhiC31 integrase-mediated transgenesis is used to insert H19 insulator flanked fragment of the Smarcd3-F6 fragment, including approximately 2.5 kb of the 5 end of the Smarcd3-F1 enhancer and Hsp68 minimal promoter followed by cre/ERT coding sequence and EF1 poly signal into the intergenic site 2 locus (Hipp11). This construct was microinjected, along with the PhiC31 integrase mRNA, into the pronuclei of zygotes collected from the TARGATT mice.

Find mice (IMSR):

Mouse Strains: 0 strains available Cell Lines: 0 lines available

Additional Tissues:

Igs2^{tm2(Smarcd3-cre/ERT2)Bbr} activity also observed in:
cardiovascular system, cavities & their linings, embryo-other, muscle

Images

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J:232545 Fig. 5 S3

Recombinase Activity

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Assays Genotypic Background Result Notes

References

All for this allele:

2 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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