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Igs2tm2(Smarcd3-cre/ERT2)Bbr - Muscle
Recombinase Activity Detail
Allele Information
Allele:
Igs2tm2(Smarcd3-cre/ERT2)Bbr
intergenic site 2; targeted mutation 2, Benoit G Bruneau
Driver: Smarcd3
Type: Targeted (Inducible, Recombinase)
Inducer: tamoxifen
Synonym: F6CreERT2, Smarcd3-F6CreERT2
Molecular description: Site-specific PhiC31 integrase-mediated transgenesis is used to insert H19 insulator flanked fragment of the Smarcd3-F6 fragment, including approximately 2.5 kb of the 5 end of the Smarcd3-F1 enhancer and Hsp68 minimal promoter followed by cre/ERT coding sequence and EF1 poly signal into the intergenic site 2 locus (Hipp11). This construct was microinjected, along with the PhiC31 integrase mRNA, into the pronuclei of zygotes collected from the TARGATT mice.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Igs2tm2(Smarcd3-cre/ERT2)Bbr activity also observed in:
cardiovascular system, cavities & their linings, embryo-other
Tissue Information
Muscle Other recombinase alleles with activity in Muscle tissues:
Images
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J:232545 Fig. 5
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory