Hlf<em1(cre/ERT2)Smoc> - Cardiovascular System Recombinase Activity Detail MGI Mouse

Hlf^{em1(cre/ERT2)Smoc} - Cardiovascular System
Recombinase Activity Detail

Allele Information | Tissue Information | Images | Recombinase Activity | References

Allele Information

Allele:

Hlf^{em1(cre/ERT2)Smoc}
hepatic leukemia factor; endonuclease-mediated mutation 1, Shanghai Model Organisms Center

Driver: Hlf
Type: Endonuclease-mediated (Conditional ready, Inducible, Recombinase)

Inducer:

tamoxifen

Synonym:

Hlf^CreER

Molecular description:

CRISPR/Cas9 genome editing technology was used to insert a 2A-Cre and rox flanked ERT2 expression cassette into the exon 4 and 3' UTR of the Hlf gene.

Find mice (IMSR):

Mouse Strains: 0 strains available Cell Lines: 0 lines available

Additional Tissues:

Hlf^{em1(cre/ERT2)Smoc} activity also observed in:
hemolymphoid system, liver & biliary system, mesenchyme

Tissue Information

Cardiovascular System

Other recombinase alleles with activity in Cardiovascular System tissues:

A1cf^{Tg(Myh6-cre/Esr1*)1Jmk}, Abcg2^{tm1.1(cre/Esr1*)Jvbe}, Aldh1l1^{em1(cre/ERT2)Nju}, Alpl^tm1(cre)Nagy ...(more)

Images

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J:312489 Fig. 4

Recombinase Activity

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Assays Genotypic Background Result Notes

References

All for this allele:

1 reference(s)

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