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Tg(Postn-icre/ERT2)#Wet - Cardiovascular System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Postn-icre/ERT2)#Wet
transgene insertion, Nina Wettschureck 		Driver: Postn
Type: Transgenic (Inducible, Recombinase)
Inducer: tamoxifen
Synonym: PnCreERT2, Postn-iCre
Molecular description: A cassette consisting of the CreERT2 cDNA followed by a polyadenylation signal from bovine growth hormone was introduced after the start codon of the mouse Postn gene carried by BAC RP23-480C1 using Red E/T-mediated recombination. After homologous recombination and Flp-mediated excision of the ampicillin cassette, the construct was injected into oocytes of C57/BL6 mice. Five founder lines were generated and characterized. The pound symbol (#) is used when no line is specified and/or lines are pooled.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(Postn-icre/ERT2)#Wet activity also observed in:
muscle
Tissue Information
Cardiovascular System Other recombinase alleles with activity in Cardiovascular System tissues:
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory