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Tg(NKX2-5*-cre)#Kyuhl - Alimentary System
Recombinase Activity Detail
Allele Information
Allele:
Tg(NKX2-5*-cre)#Kyuhl
transgene insertion, Kyu-Ho Lee 		Driver: NKX2-5
Type: Transgenic (Recombinase)
Synonym: CNkx2.5-SHFnm-cre
Molecular description: A mutated version of the chicken second heart field (SHF) NK2 homeobox 5 enhancer (cardiac activating region 3 (CAR3); nucleotides 976-3047 after transcriptional start site), where the Nkx2-5-binding consensus sequence in the BMP response element (BMPRE) was mutated from TCTGAGTG to TCTGCGAG, was used to drive the expression of the cre recombinase gene. Founder information and line numbers were not available. The pound symbol (#) is used when no line is specified and/or lines are pooled.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(NKX2-5*-cre)#Kyuhl activity also observed in:
branchial arches, cardiovascular system, mesenchyme
Tissue Information
Alimentary System Other recombinase alleles with activity in Alimentary System tissues:
Images
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J:192448 Fig. 2
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory