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Tg(Myh11-cre/ERT2)F31Gko - Cardiovascular System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Myh11-cre/ERT2)F31Gko
transgene insertion F31, Gary K Owens 		Driver: Myh11
Type: Transgenic (Inducible, Recombinase)
Inducer: tamoxifen
Synonym: Myh11-CreER(T2)-RAD, Myh11-CreERT2-RAD
Molecular description: A bacterial artificial chromosome (BAC; RP23-151J22) containing the mouse smooth muscle myosin, heavy polypeptide 11 (Myh11) gene was used to insert a cre/ERT2 sequence (a mutated human estrogen receptor ligand binding domain fused to Cre) at the start codon of Myh11. The founder line F31, in which the transgene integrated into mouse Chromosome 2 in a region devoid of other genes [Chr2:178,826,578-178,826,802 (GRCm39)], was identified.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Additional Tissues: Tg(Myh11-cre/ERT2)F31Gko activity also observed in:
muscle
Tissue Information
Cardiovascular System Other recombinase alleles with activity in Cardiovascular System tissues:
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory