About   Help   FAQ
Agrptm4.1(cre/EGFP)Rpa - Nervous System
Recombinase Activity Detail
Allele Information
Allele:
Agrptm4.1(cre/EGFP)Rpa
agouti related neuropeptide; targeted mutation 4.1, Richard D Palmiter 		Driver: Agrp
Type: Targeted (Epitope tag, Recombinase, Reporter)
Synonym: AgrpCre:GFP(version 2)
Molecular description: The targeting construct introduced a cassette containing the following features, without the nuclear localization signal, using a nonoptimal initiation codon, a cre recombinase gene fused with EGFP (cre/EGFP) with N-term sequence removed, and a myc tag with an additional 3 untranslated region from the Myc gene that promotes a short messenger RNA half-life. Flp-mediated recombination removed the FRT-flanked neomycin resistance cassette introduced downstream of the fusion gene. It is a revised "version 2" of the allele Agrptm1.1(cre/EGFP)Stei designed to have an attenuated expression of Cre:GFP.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Agrptm4.1(cre/EGFP)Rpa activity also observed in:
head
Tissue Information
Nervous System Other recombinase alleles with activity in Nervous System tissues:
Images
Drag images to compare to others or to data in the table below. Drag corners to resize images for more detail. Reset Images
J:295967 Fig. 1
Recombinase Activity
Click heading to re-sort table.
Assays Genotypic Background Result Notes  
References
All for this allele: 1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory