Fos<tm1.1(cre/folA)Mmay> - Nervous System Recombinase Activity Detail MGI Mouse

Fos^{tm1.1(cre/folA)Mmay} - Nervous System
Recombinase Activity Detail

Allele Information | Tissue Information | Images | Recombinase Activity | References

Allele Information

Allele:

Fos^{tm1.1(cre/folA)Mmay}
FBJ osteosarcoma oncogene; targeted mutation 1.1,Mark Mayford

Driver: Fos
Type: Targeted (Recombinase)

Synonym:

cfos-ddCre, c-Fos::DD-Cre, Tg(Fos-DD-Cre)

Molecular description:

A cDNA sequence encoding a mutant destabilizing form (DD) of bacterial dihydrofolate reductase (ecDHFR; folA) attached to cre recombinase cDNA was inserted into the Fos gene locus at the translation start site. Funder mice were crossed to a germline-active flpe expressing transgenic line to remove the PGK-neo cassette.

Find mice (IMSR):

Mouse Strains: 0 strains available Cell Lines: 0 lines available

Additional Tissues:

Fos^{tm1.1(cre/folA)Mmay} activity also observed in:
head

Tissue Information

Nervous System

Other recombinase alleles with activity in Nervous System tissues:

7630403G23Rik^{Tg(Th-cre)1Tmd}, Abcg2^{tm1.1(cre/Esr1*)Jvbe}, Acsm4^tm1(cre)Hsak, Adcyap1r1^{tm1.1(cre/GFP)Rpa} ...(more)

Images

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J:323567 Fig. 1

Recombinase Activity

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Assays Genotypic Background Result Notes

References

All for this allele:

2 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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