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Npfftm1.1(icre)Xen - Nervous System
Recombinase Activity Detail
Allele Information
Allele:
Npfftm1.1(icre)Xen
neuropeptide FF-amide peptide precursor; targeted mutation 1.1, Taconic Biosciences 		Driver: Npff
Type: Targeted (Recombinase)
Synonym: NPFFCre
Molecular description: Using a conventional ES cell targeting strategy and homologous recombination, the T2A peptide and the open reading frame of improved Cre recombinase (iCre) were inserted between the last amino acid and the translation termination codon in exon 3 of the Npff gene. A positive selection marker (Puromycin resistance) flanked by FRT sites was removed by crossing with germline Flpe mice.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Npfftm1.1(icre)Xen activity also observed in:
head
Tissue Information
Nervous System Other recombinase alleles with activity in Nervous System tissues:
Images
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J:334879 Fig. 1 J:334879 Fig. 2 J:334879 Fig. 3 J:334879 Fig. 4 J:334879 Fig. 5 J:334879 Fig. 6 J:334879 Fig. 8
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory