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Tg(Fgf1-RFP,-cre/ERT2)13AChiu - Cardiovascular System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Fgf1-RFP,-cre/ERT2)13AChiu
transgene insertion 13A, Ing-Ming Chiu 		Driver: Fgf1
Type: Transgenic (Inducible, Recombinase)
Synonym: F1A-CreERT2
Molecular description: The 131.5 kb transgene consists of an RFP-IRES-CreERT2polyA expression cassette inserted into a mouse bacterial artificial chromosome (BAC) clone RP23-193N23 including Fgf1 5' UTR (127.7 kb), exon 1A, and 1B sequence containing the promoter for alternatively spliced to the first protein-coding exon 1A isoform predominantly expressed in the heart. Three founders 13A, 22A, and 25A were confirmed. Line #13A with the highest expression of Cre recombinase in the heart was chosen for all the following studies.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Tissue Information
Cardiovascular System Other recombinase alleles with activity in Cardiovascular System tissues:
Images
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J:323281 Fig. 5(A) J:323281 Fig. 5(C) J:323281 Fig. 5(D) J:323281 Fig. 6
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory