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Allele Information
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Allele:
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Tg(Ccr2-cre)584Hohl
transgene insertion 584, Tobias M Hohl
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Driver: Ccr2
Type: Transgenic
(Recombinase)
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Synonym:
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CCR2-Cre
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Molecular description:
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The Cre expression cassette including the stop codon was inserted into the BAC clone RP23-182D4 containing the endogenous murine Ccr2 locus downstream of the Ccr2 promoter. The endogenous Ccr2 gene was disrupted resulting in frameshift. Four potential founder mice were identified. The lineage of one of these founders (#584) was established.
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Find mice (IMSR):
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Mouse Strains:
0 strains available
Cell Lines:
0 lines available
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Additional Tissues:
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Tg(Ccr2-cre)584Hohl activity also observed in:
hemolymphoid system,
respiratory system
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Tissue Information
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Skeletal System
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Other recombinase alleles with activity in Skeletal System tissues:
Acantm1(cre/ERT2)Crm,
Agrptm1(cre)Lowl,
Alpltm1(cre)Nagy,
Alx3em1(cre/ERT2)Lanyu,
Atoh8tm1(EGFP/cre)Gasa,
Bhlhe41em1(cre)Cya,
Cacna1htm2.1(cre)Glwn,
Calb2tm1(cre)Zjh,
Ccktm1.1(cre)Zjh,
Clec11aem3(cre/ERT2)Sjm,
Clutm2(EGFP/cre/ERT2)Wtsi,
Col10a1em1(cre)Bcgen,
Col10a1tm2.1(cre)Ksec,
Col10a1tm3.1(cre/ERT)Ksec,
Col2a1em2(dre)Smoc,
Commd10Tg(Vav1-icre)A2Kio,
Corttm1(cre)Zjh,
Crybb1em1(icre)Cln,
Ctsktm1(cre)Ska,
Cx3cr1tm1.1(cre)Jung,
Cx3cr1tm2.1(cre/ERT2)Jung,
Cx3cr1tm2.1(cre/ERT2)Litt,
Dlx5tm1(cre/ERT2)Zjh,
Dmp1tm1(cre)Msue,
Dmp1tm2(EGFP/cre/ERT2)Wtsi,
Dnttem2(icre)Trx,
E2f1Tg(Wnt1-cre)2Sor,
En1tm2(cre)Wrst,
Eporem1(cre)Bcgen,
Fgf18tm2.2(cre/ERT2)Dor,
Foxd1tm1(GFP/cre)Amc,
Gad2tm2(cre)Zjh,
Gas1em1(icre/ERT2)Nono,
Gfi1tm1(cre)Gan,
Gli1tm3(cre/ERT2)Alj,
Golm1tm2(EGFP/cre/ERT2)Wtsi,
Gt(ROSA)26Sortm1.1(rtTA,tetO-cre)Bkmn,
Gt(ROSA)26Sortm1(cre/ERT2)Tyj,
Gt(ROSA)26Sortm5(dre)Dwi,
H2az2Tg(Wnt1-cre)11Rth,
Hand2em1(dre)Pjen,
HhatTg(TFAP2A-cre)1Will,
Hhiptm1(cre/ERT2)Wtsi,
Hoxa11em1(cre/ERT2)Dmwe,
Hprt1tm1(CAG-cre)Mnn,
Hprt1tm364a(CAG-icre/ERT2)Ems,
Ifi208Tg(Cspg4-cre)1Akik,
Ihhem1(Tomm20/mKate2,dre)Xya,
Islrtm1.1(HBEGF,cre)Mat,
Islrtm2.1(cre/ERT2)Mat,
Itga8tm1.1(cre/ERT2)Jomm,
Kittm1(cre/ERT2)Dsa,
Krt17tm1(cre)Murr,
Krt19tm1(cre/ERT)Ggu,
Leprem4(dre/ERT2)Smoc,
Leprtm2(cre)Rck,
Ly6gtm2621(cre)Arte,
Lyve1tm1.1(EGFP/cre)Cys,
Mcm2tm1(cre/ERT2)Scpr,
Mecomtm4.1(cre/ERT2)Aspe,
Megf6em3(cre)Zzhg,
Mnx1tm4(cre)Tmj,
Myf5tm1.1(cre)Mrc,
Myf5tm3(cre)Sor,
Ndor1Tg(UBC-cre/ERT2)1Ejb,
Nkx3-2tm3.1(cre)Tlu,
Nkx3-2tm4.1(cre)Tlu,
Omptm4(cre)Mom,
Osr2tm2(cre)Jian,
Pax3tm1(cre)Joe,
Pax9tm1.1(cre)Sbam,
Pbx3tm1(EGFP/cre/ERT2)Wtsi,
Pdgfratm1.1(EGFP/cre/ERT2)Hyma,
Plxnd1tm2(EGFP/cre/ERT2)Wtsi,
Prg4tm1(GFP/cre/ERT2)Abl,
Prtn3tm1.1(cre/ERT2,CD4*)Wkas,
Scxtm1.1(cre)Shuk,
Shhtm1(EGFP/cre)Cjt,
Slc17a6tm2(cre)Lowl,
Slc26a9em1(cre)Sms,
Slc6a3tm1.1(cre)Bkmn,
Sp7tm1(icre)Bcgen,
Ssttm2.1(cre)Zjh,
Taglntm2(cre)Yec,
Tektm1.1(icre/Esr1*)Hrr,
Tg(Acan-cre/ERT2,-luc)1Gbg,
Tg(Acp5-cre)3Rda,
Tg(Acp5-cre)4Rda,
Tg(ACTA1-cre)79Jme,
Tg(ACTB-cre)1Tes,
Tg(Amelx-icre)854Ppap,
Tg(Amelx-icre)876Ppap,
Tg(Amh-cre)8815Reb,
Tg(BGLAP-cre)1Clem,
Tg(Bglap-cre/ERT)#Hmk,
Tg(CAG-cre/Esr1*)5Amc,
Tg(CD2-icre)4Kio,
Tg(Cdh16-cre)91Igr,
Tg(Cdh5-cre)7Mlia,
Tg(Cdh5-cre/ERT2)CIVE23Mlia,
Tg(CDX2-cre)101Erf,
Tg(Col10a1-cre)1427Vdm,
Tg(Col10a1-cre)1465Vdm,
Tg(Col10a1-cre)1466Vdm,
Tg(Col10a1-cre)1Xya,
Tg(Col10a1-cre)#Ksec,
Tg(Col11a2-cre)4Nhzi,
Tg(Col1a1-cre)1Bek,
Tg(Col1a1-cre)1Kry,
Tg(Col1a1-cre)2Bek,
Tg(Col1a1-cre/ERT2)1Crm,
Tg(Col1a1-cre/Esr1*)1Mis,
Tg(Col1a1-cre)#Xya,
Tg(Col1a2-cre)23Angl,
Tg(Col1a2-cre/ERT,-ALPP)7Cpd,
Tg(Col2a1-cre)1Asz,
Tg(Col2a1-cre)1Bhr,
Tg(Col2a1-cre)1Star,
Tg(COL2A1-cre)1Wag,
Tg(Col2a1-cre)1Xya,
Tg(Col2a1-cre/ERT)1Flng,
Tg(Col2a1-cre/ERT2)1Dic,
Tg(Col2a1-cre/ERT)KA3Smac,
Tg(Col2a1-rtTA,tetO-cre)22Pjro,
Tg(Col6a1-cre)1Gkl,
Tg(Cspg4-cre/Esr1*)BAkik,
Tg(Ctgf-cre)2Aibs,
Tg(Ctsk-cre)1Rda,
Tg(Ctsk-cre)8Rda,
Tg(Cxcl12-icre/ERT2)L289Nono,
Tg(Cyp39a1-cre)1Aibs,
Tg(Ddx4-cre)1Dcas,
Tg(Dkk3-cre/ERT2)#Mpac,
Tg(Dlx1-cre)RB27Gsat,
Tg(dlx5a-cre)1Mekk,
Tg(Dmp1-cre)1Jqfe,
Tg(EIIa-cre)C5379Lmgd,
Tg(Eno2-cre)39Jme,
Tg(Epx-EYFP/cre)#Voeh,
Tg(Fabp4-cre)1Rev,
Tg(Flt3-cre)#Ccb,
Tg(Flt3-cre/ERT2)#Ccb,
Tg(Foxa2/Sox9-cre,-lacZ)#Vleu,
Tg(Frzb-cre)1Tylz,
Tg(Gabra6-cre)B1Lfr,
Tg(Gata1-cre/ERT2)1Mym,
Tg(Gata1-cre/ERT2)2Mym,
Tg(Gata1-cre/ERT2)L245Jeng,
Tg(Gata1-cre/ERT2)L259Jeng,
Tg(Gata1-icre)1Jtp,
Tg(Gdf5-cre,-ALPP)1Kng,
Tg(Gdf5-cre/ERT2)#Mpac,
Tg(GFAP-cre)25Mes,
Tg(Gfap-cre)73.12Mvs,
Tg(Grem1-cre/ERT)3Tcw,
Tg(Grik4-cre)G32-4Stl,
Tg(Hand2-cre)7-1Clou,
Tg(HBB-cre)12Kpe,
Tg(HBB-cre)27038Kpe,
Tg(HBB-cre)27053Kpe,
Tg(Hdnr-icre)5Phg,
Tg(Hoxa5-cre)444CLjea,
Tg(Hoxa5-cre)447BLjea,
Tg(Hspa2-cre)1Eddy,
Tg(Il7-cre)CRche,
Tg(Ins2-cre)25Mgn,
Tg(Itga2b-cre)AParl,
Tg(Itga2b-cre)NE1/21Emam,
Tg(Itgax-cre)1-1Reiz,
Tg(Kdr-cre)15962Brei,
Tg(Lck-icre)3779Nik,
Tg(Lepr-cre/ERT2)#Cya,
Tg(Lepr-cre/ERT2)#Rha,
Tg(LPAR4-cre/ERT2,-EGFP)#Hjcho,
Tg(Mcpt8-icre/ERT2)#Hkar,
Tg(mI56i-cre)6-2Clou,
Tg(MMTV-cre)4Mam,
Tg(Mnx1-cre/ERT2)8Rbro,
Tg(Mpz-cre)94Imeg,
Tg(Msx2-cre/ERT2)2Nono,
Tg(Mx1-cre)1Cgn,
Tg(Myh6-cre)2182Mds,
Tg(MYOD1-cre)M23Glh,
Tg(Ncr1-cre/ERT2)#Lll,
Tg(Nes-cre)1Atp,
Tg(Nes-cre/ERT2)1Adra,
Tg(Neurog3-cre)C1Able,
Tg(Pax3-cre)1Joe,
Tg(Pcp2-cre)1Amc,
Tg(Pdgfb-icre/ERT2,-EGFP)1Frut,
Tg(Pdgfrb-cre/ERT2)6096Rha,
Tg(Pdzk1ip1-cre/ERT2)#Reiz,
Tg(Pf4-icre)Q3Rsko,
Tg(Plp1-cre/ERT2)1Ueli,
Tg(Plp1-cre/ERT)3Pop,
Tg(Postn-cre/ERT2)#Fcko,
Tg(POU3F4-cre)M51Cren,
Tg(Prdm1-cre)1Masu,
Tg(Pres-cre)1Jnz,
Tg(Prg4-cre/ERT2)#Mpac,
Tg(Prg4-cre/ERT2)#Ndy,
Tg(Prg4-cre)#Mkaz,
Tg(Prrx1-cre)1Cjt,
Tg(Pthlh-cre/ERT2)909Nono,
Tg(Relb-cre)53Rie,
Tg(REN-cre)1Haca,
Tg(Rr141-cre)1Ksec,
Tg(Rr162136-cre/ERT2)#Bpou,
Tg(Runx1/Hspa1a-cre/ERT2)#Itoy,
Tg(Runx2-icre)1Jtuc,
Tg(S100a4-cre)1Egn,
Tg(S100b-EGFP/cre/ERT2)22Amc,
Tg(Scx-cre)HShuk,
Tg(Scx-cre)LShuk,
Tg(Sim1-cre)1Lowl,
Tg(Sp7-cre/ERT2)#Hmk,
Tg(Sp7-tTA,tetO-EGFP/cre)1Amc,
Tg(Stra8-icre)1Reb,
Tg(Syn1-cre)671Jxm,
Tg(Tagln-cre)1Her,
Tg(Tek-cre)1Ywa,
Tg(Thy1-cre)1Vln,
Tg(TSPY1-cre)33aYfcl,
Tg(Vav1-cre)1Cgp,
Tg(Wfs1-cre/ERT2)3Aibs,
Tlr2tm1(cre)Dfil,
Tnfsf11em2(cre)Htaka,
Trpv4em1(cre/ERT2)Amc,
Twist2tm1.1(cre)Dor,
Twist2tm1(cre)Dor,
Wt1tm1(EGFP/cre)Wtp
(less)
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Images
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J:341212
Fig. 3
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Recombinase Activity
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Assays
Genotypic Background
Result Notes
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References
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