Mlc1<tm2.1(cre/ERT2)Jhmc> - Nervous System Recombinase Activity Detail MGI Mouse

Mlc1^{tm2.1(cre/ERT2)Jhmc} - Nervous System
Recombinase Activity Detail

Allele Information | Tissue Information | Images | Recombinase Activity | References

Allele Information

Allele:

Mlc1^{tm2.1(cre/ERT2)Jhmc}
megalencephalic leukoencephalopathy with subcortical cysts 1 homolog (human); targeted mutation 2.1, Joseph H McCarty

Driver: Mlc1
Type: Targeted (Inducible, Recombinase)

Inducer:

tamoxifen

Synonym:

MLCT

Molecular description:

The T2A-CreERT2 cassette was inserted immediately upstream of the endogenous stop codon in the exon 12 of the Mlc1 gene in frame. The FRT flanked Neo selection cassette was inserted 116 bp downstream of the 3' UTR. The Neo cassette in the targeting vector was removed during ES clone expansion.

Find mice (IMSR):

Mouse Strains: 0 strains available Cell Lines: 0 lines available

Additional Tissues:

Mlc1^{tm2.1(cre/ERT2)Jhmc} activity also observed in:
head, sensory organs

Tissue Information

Nervous System

Other recombinase alleles with activity in Nervous System tissues:

7630403G23Rik^{Tg(Th-cre)1Tmd}, Abcg2^{tm1.1(cre/Esr1*)Jvbe}, Acsm4^tm1(cre)Hsak, Adcyap1r1^{tm1.1(cre/GFP)Rpa} ...(more)

Images

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J:341452 Fig. 2

J:341452 Fig. 3

J:341452 Fig. 4

Recombinase Activity

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Assays Genotypic Background Result Notes

References

All for this allele:

1 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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