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Sequence Detail
ID/Version
A2AGL3 Q60836 Q62198 Q62175 Q9QY91 P70184 P70185 Q4JFC4 Q3V1H0 (UniProt | EBI) Last sequence update: 2008-02-05
Last annotation update: 2024-07-24
Sequence
description
from provider
RecName: Full=Ryanodine receptor 3 {ECO:0000305|PubMed:8702664}; Short=RYR-3; Short=RyR3;AltName: Full=Brain ryanodine receptor-calcium release channel;AltName: Full=Brain-type ryanodine receptor;AltName: Full=Type 3 ryanodine receptor;
Provider SWISS-PROT
Sequence
Polypeptide 4863 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Ryr3 ryanodine receptor 3 32 112 3 12
Sequence references in MGI J:23314 Giannini G, et al., The ryanodine receptor/calcium channel genes are widely and differentially expressed in murine brain and peripheral tissues. J Cell Biol. 1995 Mar;128(5):893-904
J:26886 Takeshima H, et al., Ca(2+)-induced Ca2+ release in myocytes from dyspedic mice lacking the type-1 ryanodine receptor. EMBO J. 1995 Jul 3;14(13):2999-3006
J:34908 Takeshima H, et al., Generation and characterization of mutant mice lacking ryanodine receptor type 3. J Biol Chem. 1996 Aug 16;271(33):19649-52
J:72345 Yang D, et al., RyR3 amplifies RyR1-mediated Ca(2+)-induced Ca(2+) release in neonatal mammalian skeletal muscle. J Biol Chem. 2001 Oct 26;276(43):40210-4
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:114233 Sonnleitner A, et al., Functional properties of the ryanodine receptor type 3 (RyR3) Ca2+ release channel. EMBO J. 1998 May 15;17(10):2790-8
J:115420 Lohn M, et al., Regulation of calcium sparks and spontaneous transient outward currents by RyR3 in arterial vascular smooth muscle cells. Circ Res. 2001 Nov 23;89(11):1051-7
J:180423 Matsuo N, et al., Comprehensive behavioral phenotyping of ryanodine receptor type 3 (RyR3) knockout mice: decreased social contact duration in two social interaction tests. Front Behav Neurosci. 2009;3:3
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
09/17/2024
MGI 6.24
The Jackson Laboratory