ID/Version |
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Sequence description from provider |
RecName: Full=E3 ubiquitin-protein ligase RNF213; EC=2.3.2.27 {ECO:0000250|UniProtKB:Q63HN8}; EC=3.6.4.- {ECO:0000269|PubMed:32573437};AltName: Full=E3 ubiquitin-lipopolysaccharide ligase RNF213 {ECO:0000305}; EC=2.3.2.- {ECO:00002 | ||||||||||||||
Provider | SWISS-PROT | ||||||||||||||
Sequence |
Polypeptide
5148
aa
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Annotated genes and markers |
Follow the symbol links to get more information on the GO terms,
expression assays, orthologs, phenotypic alleles, and other information
for the genes or markers below.
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Sequence references in MGI |
J:99680
The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:200802 Kobayashi H, et al., Ablation of Rnf213 retards progression of diabetes in the Akita mouse. Biochem Biophys Res Commun. 2013 Mar 15;432(3):519-25 J:227953 Sonobe S, et al., Temporal profile of the vascular anatomy evaluated by 9.4-T magnetic resonance angiography and histopathological analysis in mice lacking RNF213: a susceptibility gene for moyamoya disease. Brain Res. 2014 Mar 13;1552:64-71 J:228851 Sonobe S, et al., Increased vascular MMP-9 in mice lacking RNF213: moyamoya disease susceptibility gene. Neuroreport. 2014 Dec 17;25(18):1442-6 J:229327 Kobayashi H, et al., Biochemical and Functional Characterization of RNF213 (Mysterin) R4810K, a Susceptibility Mutation of Moyamoya Disease, in Angiogenesis In Vitro and In Vivo. J Am Heart Assoc. 2015 Jul;4(7) J:229422 Kanoke A, et al., Temporal profile of the vascular anatomy evaluated by 9.4-tesla magnetic resonance angiography and histological analysis in mice with the R4859K mutation of RNF213, the susceptibility gene for moyamoya disease. Brain Res. 2015 Oct 22;1624:497-505 J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89 J:308425 Houzelstein D, et al., The ring finger protein 213 gene (Rnf213) contributes to Rift Valley fever resistance in mice. Mamm Genome. 2021 Feb;32(1):30-37 J:308514 Ahel J, et al., Moyamoya disease factor RNF213 is a giant E3 ligase with a dynein-like core and a distinct ubiquitin-transfer mechanism. Elife. 2020 Jun 23;9:e56185 J:313855 Otten EG, et al., Ubiquitylation of lipopolysaccharide by RNF213 during bacterial infection. Nature. 2021 Jun;594(7861):111-116 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 09/17/2024 MGI 6.24 |
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