Sequence Detail

ID/Version

O88738 Q69ZM5 Q8BNX0 Q8BR72 Q8BRV7 E9PYU6 Q8C737 (UniProt | EBI)

Last sequence update: 2012-03-21
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Baculoviral IAP repeat-containing protein 6; EC=2.3.2.27 {ECO:0000269|PubMed:15300255};AltName: Full=BIR repeat-containing ubiquitin-conjugating enzyme; Short=BRUCE;AltName: Full=RING-type E3 ubiquitin transferase BIRC6 {ECO:

Provider

SWISS-PROT

Sequence

Polypeptide 4882 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Birc6	baculoviral IAP repeat-containing 6	38	105	3	66

Sequence references in MGI

J:48143 Hauser HP, et al., A giant ubiquitin-conjugating enzyme related to IAP apoptosis inhibitors. J Cell Biol. 1998 Jun 15;141(6):1415-22
J:92575 Okazaki N, et al., Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. DNA Res. 2004 Jun 30;11(3):205-18
J:94169 Lotz K, et al., BRUCE, a giant E2/E3 ubiquitin ligase and inhibitor of apoptosis protein of the trans-Golgi network, is required for normal placenta development and mouse survival. Mol Cell Biol. 2004 Nov;24(21):9339-50
J:96768 Hao Y, et al., Apollon ubiquitinates SMAC and caspase-9, and has an essential cytoprotection function. Nat Cell Biol. 2004 Sep;6(9):849-60
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89