Sequence Detail

ID/Version

O88910 E9Q5S2 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=MAGUK p55 subfamily member 3 {ECO:0000305};AltName: Full=Discs large homolog 3;AltName: Full=Protein MPP3;

Provider

SWISS-PROT

Sequence

Polypeptide 568 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Mpp3	membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)	11	100	4	12

Sequence references in MGI

J:48003 Lin L, et al., cDNA sequence and chromosomal localization of mouse Dlgh3 gene adjacent to the BRCA1 tumor suppressor locus. Biochim Biophys Acta. 1998 Nov 26;1443(1-2):211-6
J:93572 Joubert L, et al., New sorting nexin (SNX27) and NHERF specifically interact with the 5-HT4(a) receptor splice variant: roles in receptor targeting. J Cell Sci. 2004 Oct 15;117(Pt 22):5367-79
J:117972 Gavarini S, et al., Opposite effects of PSD-95 and MPP3 PDZ proteins on serotonin 5-hydroxytryptamine2C receptor desensitization and membrane stability. Mol Biol Cell. 2006 Nov;17(11):4619-31
J:198427 Dudok JJ, et al., MPP3 is required for maintenance of the apical junctional complex, neuronal migration, and stratification in the developing cortex. J Neurosci. 2013 May 8;33(19):8518-27
J:199562 Dudok JJ, et al., MPP3 regulates levels of PALS1 and adhesion between photoreceptors and Muller cells. Glia. 2013 Oct;61(10):1629-44
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:333121 Becamel C, et al., The serotonin 5-HT2A and 5-HT2C receptors interact with specific sets of PDZ proteins. J Biol Chem. 2004 May 7;279(19):20257-66
J:333179 Kantardzhieva A, et al., MPP3 is recruited to the MPP5 protein scaffold at the retinal outer limiting membrane. FEBS J. 2006 Mar;273(6):1152-65