Sequence Detail

ID/Version

P0DOV2 Q8C4X3 Q3UCH9 Q921V9 P15092 B7ZNS3 Q3TM07 Q08619 Q3U7F4 Q3U7K5 Q3U776 (UniProt | EBI)

Last sequence update: 2016-11-02
Last annotation update: 2024-05-29

Sequence description from provider

RecName: Full=Interferon-activable protein 204; Short=Ifi-204;AltName: Full=Interferon-inducible protein p204;

Provider

SWISS-PROT

Sequence

Polypeptide 619 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Ifi204	interferon activated gene 204	38	98	4	13
Gene	Ifi211	interferon activated gene 211	26	98	4	6

Sequence references in MGI

J:10055 Choubey D, et al., Interferons as gene activators. Indications for repeated gene duplication during the evolution of a cluster of interferon-activatable genes on murine chromosome 1. J Biol Chem. 1989 Oct 15;264(29):17182-9
J:96487 Liu CJ, et al., The interferon-inducible p204 protein acts as a transcriptional coactivator of Cbfa1 and enhances osteoblast differentiation. J Biol Chem. 2005 Jan 28;280(4):2788-96
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:106897 Asefa B, et al., p205, a potential tumor suppressor, inhibits cell proliferation via multiple pathways of cell cycle regulation. FEBS Lett. 2006 Feb 20;580(5):1205-14
J:113475 Ding B, et al., p204 is required for the differentiation of P19 murine embryonal carcinoma cells to beating cardiac myocytes: its expression is activated by the cardiac Gata4, Nkx2.5, and Tbx5 proteins. J Biol Chem. 2006 May 26;281(21):14882-92
J:113476 Ding B, et al., p204 protein overcomes the inhibition of the differentiation of P19 murine embryonal carcinoma cells to beating cardiac myocytes by Id proteins. J Biol Chem. 2006 May 26;281(21):14893-906
J:233939 Dauffy J, et al., The interferon-inducible gene, Ifi204, is transcriptionally activated in response to M-CSF, and its expression favors macrophage differentiation in myeloid progenitor cells. J Leukoc Biol. 2006 Jan;79(1):173-83
J:284439 Chen W, et al., DNA Sensor IFI204 Contributes to Host Defense Against Staphylococcus aureus Infection in Mice. Front Immunol. 2019;10:474
J:339048 Storek KM, et al., cGAS and Ifi204 cooperate to produce type I IFNs in response to Francisella infection. J Immunol. 2015 Apr 1;194(7):3236-45