Sequence Detail

ID/Version

P13020 Q3UPB1 Q8R590 (UniProt | EBI)

Last sequence update: 2003-02-12
Last annotation update: 2024-05-29

Sequence description from provider

RecName: Full=Gelsolin;AltName: Full=Actin-depolymerizing factor; Short=ADF;AltName: Full=Brevin;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 780 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Gsn	gelsolin	104	120	4	14

Sequence references in MGI

J:9903 Dieffenbach CW, et al., Cloning of murine gelsolin and its regulation during differentiation of embryonal carcinoma cells. J Biol Chem. 1989 Aug 5;264(22):13281-8
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:187314 Irving AT, et al., Regulation of actin dynamics by protein kinase R control of gelsolin enforces basal innate immune defense. Immunity. 2012 May 25;36(5):795-806
J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:347151 Kuwabara Y, et al., A human FLII gene variant alters sarcomeric actin thin filament length and predisposes to cardiomyopathy. Proc Natl Acad Sci U S A. 2023 May 9;120(19):e2213696120