Sequence Detail

ID/Version

P18572 Q7TSC0 Q6LDB0 (UniProt | EBI)

Last sequence update: 2004-08-31
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Basigin;AltName: Full=Basic immunoglobulin superfamily;AltName: Full=HT7 antigen;AltName: Full=Membrane glycoprotein gp42;AltName: CD_antigen=CD147;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 389 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Bsg	basigin	55	123	3	15

Sequence references in MGI

J:10365 Altruda F, et al., Cloning of cDNA for a novel mouse membrane glycoprotein (gp42): shared identity to histocompatibility antigens, immunoglobulins and neural-cell adhesion molecules. Gene. 1989 Dec 28;85(2):445-51
J:10584 Miyauchi T, et al., Basigin, a new, broadly distributed member of the immunoglobulin superfamily, has strong homology with both the immunoglobulin V domain and the beta-chain of major histocompatibility complex class II antigen. J Biochem. 1990 Feb;107(2):316-23
J:11165 Kanekura T, et al., Basigin, a new member of the immunoglobulin superfamily: genes in different mammalian species, glycosylation changes in the molecule from adult organs and possible variation in the N-terminal sequences. Cell Struct Funct. 1991 Feb;16(1):23-30
J:29726 Miyauchi T, et al., Structure of the mouse basigin gene, a unique member of the immunoglobulin superfamily. J Biochem. 1995 Oct;118(4):717-24
J:64198 Hori K, et al., Retinal dysfunction in basigin deficiency. Invest Ophthalmol Vis Sci. 2000 Sep;41(10):3128-33
J:68358 Ochrietor JD, et al., Retinal degeneration following failed photoreceptor maturation in 5A11/basigin null mice. Exp Eye Res. 2001 Apr;72(4):467-77
J:75560 Saxena DK, et al., Behaviour of a sperm surface transmembrane glycoprotein basigin during epididymal maturation and its role in fertilization in mice. Reproduction. 2002 Mar;123(3):435-44
J:88590 Clamp MF, et al., Developmental analyses of 5A11/Basigin, 5A11/Basigin-2 and their putative binding partner MCT1 in the mouse eye. Exp Eye Res. 2004 Apr;78(4):777-89
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:103738 Ochrietor JD, et al., Inactivation of the Basigin gene impairs normal retinal development and maturation. Vision Res. 2002 Feb;42(4):447-53
J:119441 Philp NJ, et al., Loss of MCT1, MCT3, and MCT4 expression in the retinal pigment epithelium and neural retina of the 5A11/basigin-null mouse. Invest Ophthalmol Vis Sci. 2003 Mar;44(3):1305-11
J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:199573 Bi J, et al., Basigin null mutant male mice are sterile and exhibit impaired interactions between germ cells and Sertoli cells. Dev Biol. 2013 Aug 15;380(2):145-56
J:235607 Suzuki J, et al., Xkr8 phospholipid scrambling complex in apoptotic phosphatidylserine exposure. Proc Natl Acad Sci U S A. 2016 Aug 23;113(34):9509-14
J:289091 Ait-Ali N, et al., Rod-derived cone viability factor promotes cone survival by stimulating aerobic glycolysis. Cell. 2015 May 7;161(4):817-32
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:326084 Ochrietor JD, et al., Retina-specific expression of 5A11/Basigin-2, a member of the immunoglobulin gene superfamily. Invest Ophthalmol Vis Sci. 2003 Sep;44(9):4086-96
J:326231 Mannowetz N, et al., Basigin interacts with both MCT1 and MCT2 in murine spermatozoa. J Cell Physiol. 2012 May;227(5):2154-62