Sequence Detail

ID/Version

P19221 (UniProt | EBI)

Last sequence update: 1990-11-01
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Prothrombin; EC=3.4.21.5;AltName: Full=Coagulation factor II;Contains: RecName: Full=Activation peptide fragment 1;Contains: RecName: Full=Activation peptide fragment 2;Contains: RecName: Full=Thrombin light chain;Contains: RecNa

Provider

SWISS-PROT

Sequence

Polypeptide 618 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	F2	coagulation factor II	76	116	3	16

Sequence references in MGI

J:23 Banfield DK, et al., Partial characterization of vertebrate prothrombin cDNAs: amplification and sequence analysis of the B chain of thrombin from nine different species. Proc Natl Acad Sci U S A. 1992 Apr 1;89(7):2779-83
J:10794 Degen SJ, et al., Characterization of the cDNA coding for mouse prothrombin and localization of the gene on mouse chromosome 2. DNA Cell Biol. 1990 Sep;9(7):487-98
J:122778 Marino F, et al., Structural basis of Na+ activation mimicry in murine thrombin. J Biol Chem. 2007 Jun 1;282(22):16355-61
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89