Sequence Detail

ID/Version

P33175 Q9Z2F9 Q6PDY7 Q5DTP1 (UniProt | EBI)

Last sequence update: 2006-06-27
Last annotation update: 2024-05-29

Sequence description from provider

RecName: Full=Kinesin heavy chain isoform 5A;AltName: Full=Kinesin heavy chain neuron-specific 1;AltName: Full=Neuronal kinesin heavy chain; Short=NKHC;

Provider

SWISS-PROT

Sequence

Polypeptide 1027 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Kif5a	kinesin family member 5A	50	103	4	15

Sequence references in MGI

J:3448 Aizawa H, et al., Kinesin family in murine central nervous system. J Cell Biol. 1992 Dec;119(5):1287-96
J:50344 Xia Ch, et al., Chromosomal localization reveals three kinesin heavy chain genes in mouse. Genomics. 1998 Sep 1;52(2):209-13
J:82911 Xia CH, et al., Abnormal neurofilament transport caused by targeted disruption of neuronal kinesin heavy chain KIF5A. J Cell Biol. 2003 Apr 14;161(1):55-66
J:86976 Macioce P, et al., Beta-dystrobrevin interacts directly with kinesin heavy chain in brain. J Cell Sci. 2003 Dec 1;116(Pt 23):4847-56
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:137197 Dictenberg JB, et al., A direct role for FMRP in activity-dependent dendritic mRNA transport links filopodial-spine morphogenesis to fragile X syndrome. Dev Cell. 2008 Jun;14(6):926-39
J:215725 Ohnishi T, et al., Identification and characterization of a neuron-specific isoform of protrudin. Genes Cells. 2014 Feb;19(2):97-111
J:235257 Matsuzaki F, et al., Protrudin serves as an adaptor molecule that connects KIF5 and its cargoes in vesicular transport during process formation. Mol Biol Cell. 2011 Dec;22(23):4602-20
J:238467 Setou M, et al., Glutamate-receptor-interacting protein GRIP1 directly steers kinesin to dendrites. Nature. 2002 May 02;417(6884):83-7
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89