Sequence Detail

ID/Version

P33609 (UniProt | EBI)

Last sequence update: 1994-06-01
Last annotation update: 2024-05-29

Sequence description from provider

RecName: Full=DNA polymerase alpha catalytic subunit; EC=2.7.7.7 {ECO:0000269|PubMed:8026492, ECO:0000269|PubMed:8253737};AltName: Full=DNA polymerase alpha catalytic subunit p180;

Provider

SWISS-PROT

Sequence

Polypeptide 1465 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Pola1	polymerase (DNA directed), alpha 1	73	97	3	23

Sequence references in MGI

J:4544 Miyazawa H, et al., Molecular cloning of the cDNAs for the four subunits of mouse DNA polymerase alpha-primase complex and their gene expression during cell proliferation and the cell cycle. J Biol Chem. 1993 Apr 15;268(11):8111-22
J:17170 Izumi M, et al., Identification of a point mutation in the cDNA of the catalytic subunit of DNA polymerase alpha from a temperature-sensitive mouse FM3A cell line. J Biol Chem. 1994 Mar 11;269(10):7639-44
J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:297455 Stadlbauer F, et al., DNA replication in vitro by recombinant DNA-polymerase-alpha-primase. Eur J Biochem. 1994 Jun 15;222(3):781-93