Sequence Detail

ID/Version

P42682 (UniProt | EBI)

Last sequence update: 1995-11-01
Last annotation update: 2024-05-29

Sequence description from provider

RecName: Full=Tyrosine-protein kinase TXK; EC=2.7.10.2;AltName: Full=PTK-RL-18;AltName: Full=Resting lymphocyte kinase;

Provider

SWISS-PROT

Sequence

Polypeptide 527 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Txk	TXK tyrosine kinase	27	103	3	11

Sequence references in MGI

J:22509 Hu Q, et al., Identification of Rlk, a novel protein tyrosine kinase with predominant expression in the T cell lineage. J Biol Chem. 1995 Jan 27;270(4):1928-34
J:27414 Sommers CL, et al., Murine txk: a protein tyrosine kinase gene regulated by T cell activation. Oncogene. 1995 Jul 20;11(2):245-51
J:27723 Haire RN, et al., The murine form of TXK, a novel TEC kinase expressed in thymus maps to chromosome 5. Mamm Genome. 1995 Jul;6(7):476-80
J:58493 Sommers CL, et al., A role for the Tec family tyrosine kinase Txk in T cell activation and thymocyte selection. J Exp Med. 1999 Nov 15;190(10):1427-38
J:64938 Rajagopal K, et al., RIBP, a novel Rlk/Txk- and itk-binding adaptor protein that regulates T cell activation. J Exp Med. 1999 Dec 6;190(11):1657-68
J:140737 Sahu N, et al., Selective expression rather than specific function of Txk and Itk regulate Th1 and Th2 responses. J Immunol. 2008 Nov 1;181(9):6125-31