Sequence Detail

ID/Version

P56371 Q3TSQ6 (UniProt | EBI)

Last sequence update: 2013-03-06
Last annotation update: 2024-05-29

Sequence description from provider

RecName: Full=Ras-related protein Rab-4A; EC=3.6.5.2 {ECO:0000250|UniProtKB:P20338};

Provider

SWISS-PROT

Sequence

Polypeptide 218 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Rab4a	RAB4A, member RAS oncogene family	41	100	3	8

Sequence references in MGI

J:37471 Ikeda H, et al., Isolation and sequence determination of cDNA encoding mouse rab 4 and candidate approach for the beige mutation in mice. Biochem Mol Biol Int. 1996 Nov;40(4):647-51
J:79316 Cormont M, et al., A FYVE-finger-containing protein, Rabip4, is a Rab4 effector involved in early endosomal traffic. Proc Natl Acad Sci U S A. 2001 Feb 13;98(4):1637-42
J:87273 Walther DJ, et al., Serotonylation of small GTPases is a signal transduction pathway that triggers platelet alpha-granule release. Cell. 2003 Dec 26;115(7):851-62
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:123368 Itoh T, et al., Screening for target Rabs of TBC (Tre-2/Bub2/Cdc16) domain-containing proteins based on their Rab-binding activity. Genes Cells. 2006 Sep;11(9):1023-37
J:125105 Yang H, et al., Identification of three novel proteins (SGSM1, 2, 3) which modulate small G protein (RAP and RAB)-mediated signaling pathway. Genomics. 2007 Aug;90(2):249-60
J:156668 Hoogenraad CC, et al., Neuron specific Rab4 effector GRASP-1 coordinates membrane specialization and maturation of recycling endosomes. PLoS Biol. 2010;8(1):e1000283
J:235260 Kloer DP, et al., Assembly of the biogenesis of lysosome-related organelles complex-3 (BLOC-3) and its interaction with Rab9. J Biol Chem. 2010 Mar 5;285(10):7794-804
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89