Sequence Detail

ID/Version

P70227 Q5DWM4 Q8CED5 Q91Z08 (UniProt | EBI)

Last sequence update: 2005-10-25
Last annotation update: 2024-05-29

Sequence description from provider

RecName: Full=Inositol 1,4,5-trisphosphate receptor type 3;AltName: Full=IP3 receptor isoform 3; Short=IP3R 3; Short=InsP3R3;AltName: Full=Type 3 inositol 1,4,5-trisphosphate receptor; Short=Type 3 InsP3 receptor;

Provider

SWISS-PROT

Sequence

Polypeptide 2670 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Itpr3	inositol 1,4,5-triphosphate receptor 3	63	102	3	41

Sequence references in MGI

J:2208 Ross CA, et al., Three additional inositol 1,4,5-trisphosphate receptors: molecular cloning and differential localization in brain and peripheral tissues. Proc Natl Acad Sci U S A. 1992 May 15;89(10):4265-9
J:59593 De Smedt H, et al., Isoform diversity of the inositol trisphosphate receptor in cell types of mouse origin. Biochem J. 1997 Mar 1;322(Pt 2):575-83
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:166717 Giorgi C, et al., PML regulates apoptosis at endoplasmic reticulum by modulating calcium release. Science. 2010 Nov 26;330(6008):1247-51
J:170219 Yamazaki H, et al., Tyr-167/Trp-168 in type 1/3 inositol 1,4,5-trisphosphate receptor mediates functional coupling between ligand binding and channel opening. J Biol Chem. 2010 Nov 12;285(46):36081-91
J:203403 Shindo Y, et al., Lrmp/Jaw1 is expressed in sweet, bitter, and umami receptor-expressing cells. Chem Senses. 2010 Feb;35(2):171-7
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89