Sequence Detail

ID/Version

Q09LZ8 A6PWC6 Q09LZ9 A2A979 A6PWC5 (UniProt | EBI)

Last sequence update: 2006-10-17
Last annotation update: 2024-05-29

Sequence description from provider

RecName: Full=Cytosolic carboxypeptidase 6 {ECO:0000303|PubMed:21074048}; EC=3.4.17.- {ECO:0000269|PubMed:21074048, ECO:0000269|PubMed:25103237, ECO:0000269|PubMed:26829768, ECO:0000269|PubMed:29593216}; EC=3.4.17.24 {ECO:0000269|PubMed:21

Provider

SWISS-PROT

Sequence

Polypeptide 540 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Agbl4	ATP/GTP binding protein-like 4	30	98	3	8

Sequence references in MGI

J:166837 Rogowski K, et al., A family of protein-deglutamylating enzymes associated with neurodegeneration. Cell. 2010 Nov 12;143(4):564-78
J:168198 Kalinina E, et al., A novel subfamily of mouse cytosolic carboxypeptidases. FASEB J. 2007 Mar;21(3):836-50
J:215911 Tort O, et al., The cytosolic carboxypeptidases CCP2 and CCP3 catalyze posttranslational removal of acidic amino acids. Mol Biol Cell. 2014 Oct 1;25(19):3017-27
J:231311 Xia P, et al., Glutamylation of the DNA sensor cGAS regulates its binding and synthase activity in antiviral immunity. Nat Immunol. 2016 Apr;17(4):369-78
J:259707 Ye B, et al., Klf4 glutamylation is required for cell reprogramming and early embryonic development in mice. Nat Commun. 2018 Mar 28;9(1):1261