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Sequence Detail
ID/Version
Q3LRV9 Q3LRW0 A6XA78 E9Q825 (UniProt | EBI) Last sequence update: 2005-10-25
Last annotation update: 2024-05-29
Sequence
description
from provider
RecName: Full=Trem-like transcript 4 protein; Short=TLT-4;AltName: Full=Triggering receptor expressed on myeloid cells-like protein 3;AltName: Full=Triggering receptor expressed on myeloid cells-like protein 4;Flags: Precursor;
Provider SWISS-PROT
Sequence
Polypeptide 263 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Treml4 triggering receptor expressed on myeloid cells-like 4 18 96 2 5
Sequence references in MGI J:144335 Hemmi H, et al., A new triggering receptor expressed on myeloid cells (Trem) family member, Trem-like 4, binds to dead cells and is a DNAX activation protein 12-linked marker for subsets of mouse macrophages and dendritic cells. J Immunol. 2009 Feb 1;182(3):1278-86
J:180744 Hemmi H, et al., Treml4, an Ig superfamily member, mediates presentation of several antigens to T cells in vivo, including protective immunity to HER2 protein. J Immunol. 2012 Feb 1;188(3):1147-55
J:231858 Ramirez-Ortiz ZG, et al., The receptor TREML4 amplifies TLR7-mediated signaling during antiviral responses and autoimmunity. Nat Immunol. 2015 May;16(5):495-504

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
06/12/2024
MGI 6.13
The Jackson Laboratory