Sequence Detail

ID/Version

Q3U9G9 Q8BST3 Q91YS5 Q811V9 Q811V8 Q8K2Y8 Q8VDM0 Q91Z27 Q3TSW2 (UniProt | EBI)

Last sequence update: 2006-03-21
Last annotation update: 2024-05-29

Sequence description from provider

RecName: Full=Delta(14)-sterol reductase LBR; Short=Delta-14-SR; EC=1.3.1.70 {ECO:0000250|UniProtKB:Q14739};AltName: Full=3-beta-hydroxysterol Delta (14)-reductase {ECO:0000303|PubMed:18785926};AltName: Full=C-14 sterol reductase;

Provider

SWISS-PROT

Sequence

Polypeptide 626 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Lbr	lamin B receptor	34	102	3	35

Sequence references in MGI

J:80915 Shultz LD, et al., Mutations at the mouse ichthyosis locus are within the lamin B receptor gene: a single gene model for human Pelger-Huet anomaly. Hum Mol Genet. 2003 Jan 1;12(1):61-9
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:143116 Bennati AM, et al., Disruption of the gene encoding 3beta-hydroxysterol Delta-reductase (Tm7sf2) in mice does not impair cholesterol biosynthesis. FEBS J. 2008 Oct;275(20):5034-47
J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:180894 Subramanian G, et al., Lamin B receptor regulates the growth and maturation of myeloid progenitors via its sterol reductase domain: implications for cholesterol biosynthesis in regulating myelopoiesis. J Immunol. 2012 Jan 1;188(1):85-102
J:277871 Xu M, et al., Clnk plays a role in TNF-alpha-induced cell death in murine fibrosarcoma cell line L929. Biochem Biophys Res Commun. 2015 Jul 31;463(3):275-9
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89