Sequence Detail

ID/Version

Q60805 Q62194 (UniProt | EBI)

Last sequence update: 1996-11-01
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Tyrosine-protein kinase Mer; EC=2.7.10.1;AltName: Full=Proto-oncogene c-Mer;AltName: Full=Receptor tyrosine kinase MerTK;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 994 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Mertk	MER proto-oncogene tyrosine kinase	47	106	3	22

Sequence references in MGI

J:26233 Graham DK, et al., Cloning and developmental expression analysis of the murine c-mer tyrosine kinase. Oncogene. 1995 Jun 15;10(12):2349-59
J:54681 Lu Q, et al., Tyro-3 family receptors are essential regulators of mammalian spermatogenesis. Nature. 1999 Apr 22;398(6729):723-8
J:95627 Wu Y, et al., A role for Mer tyrosine kinase in {alpha}v{beta}5 integrin-mediated phagocytosis of apoptotic cells. J Cell Sci. 2005 Feb 1;118(Pt 3):539-553
J:115680 Behrens EM, et al., The mer receptor tyrosine kinase: expression and function suggest a role in innate immunity. Eur J Immunol. 2003 Aug;33(8):2160-7
J:167178 Caberoy NB, et al., Tubby and tubby-like protein 1 are new MerTK ligands for phagocytosis. EMBO J. 2010 Dec 1;29(23):3898-910
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89