Sequence Detail

ID/Version

Q60992 A2AH49 (UniProt | EBI)

Last sequence update: 1997-11-01
Last annotation update: 2024-05-29

Sequence description from provider

RecName: Full=Guanine nucleotide exchange factor VAV2; Short=VAV-2;

Provider

SWISS-PROT

Sequence

Polypeptide 868 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Vav2	vav 2 oncogene	23	107	3	15

Sequence references in MGI

J:34491 Schuebel KE, et al., Isolation and characterization of murine vav2, a member of the vav family of proto-oncogenes. Oncogene. 1996 Jul 18;13(2):363-71
J:110334 Hunter SG, et al., Essential role of Vav family guanine nucleotide exchange factors in EphA receptor-mediated angiogenesis. Mol Cell Biol. 2006 Jul;26(13):4830-42
J:180687 Fukumoto Y, et al., Role of scaffold protein afadin dilute domain-interacting protein (ADIP) in platelet-derived growth factor-induced cell movement by activating Rac protein through Vav2 protein. J Biol Chem. 2011 Dec 16;286(50):43537-48
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89