ID/Version |
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Sequence description from provider |
RecName: Full=Mothers against decapentaplegic homolog 2; Short=MAD homolog 2; Short=Mothers against DPP homolog 2;AltName: Full=Mad-related protein 2; Short=mMad2;AltName: Full=SMAD family member 2; Short=SMAD 2; Sh | ||||||||||||||
Provider | SWISS-PROT | ||||||||||||||
Sequence |
Polypeptide
467
aa
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Annotated genes and markers |
Follow the symbol links to get more information on the GO terms,
expression assays, orthologs, phenotypic alleles, and other information
for the genes or markers below.
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Sequence references in MGI |
J:34765
Baker JC, et al., A novel mesoderm inducer, Madr2, functions in the activin signal transduction pathway. Genes Dev. 1996 Aug 1;10(15):1880-9
J:43006 Devereux TR, et al., Smad4 (homolog of human DPC4) and Smad2 (homolog of human JV18-1): candidates for murine lung tumor resistance and suppressor genes. Carcinogenesis. 1997 Sep;18(9):1751-5 J:60559 Shoji H, et al., Identification and characterization of a PDZ protein that interacts with activin type II receptors. J Biol Chem. 2000 Feb 25;275(8):5485-92 J:61302 Weinstein M, et al., Functions of mammalian Smad genes as revealed by targeted gene disruption in mice. Cytokine Growth Factor Rev. 2000 Mar-Jun;11(1-2):49-58 J:65990 Miura S, et al., Hgs (Hrs), a FYVE domain protein, is involved in smad signaling through cooperation with SARA. Mol Cell Biol. 2000 Dec;20(24):9346-55 J:79484 Jiao K, et al., Identification of mZnf8, a Mouse Kruppel-Like Transcriptional Repressor, as a Novel Nuclear Interaction Partner of Smad1. Mol Cell Biol. 2002 Nov;22(21):7633-44 J:92664 Lin HK, et al., Cytoplasmic PML function in TGF-beta signalling. Nature. 2004 Sep 9;431(7005):205-11 J:95374 Dunn NR, et al., Mice exclusively expressing the short isoform of Smad2 develop normally and are viable and fertile. Genes Dev. 2005 Jan 1;19(1):152-63 J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563 J:122005 Mavrakis KJ, et al., Arkadia Enhances Nodal/TGF-beta Signaling by Coupling Phospho-Smad2/3 Activity and Turnover. PLoS Biol. 2007 Mar 6;5(3):e67 J:169049 Varelas X, et al., The Crumbs complex couples cell density sensing to Hippo-dependent control of the TGF-beta-SMAD pathway. Dev Cell. 2010 Dec 14;19(6):831-44 J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89 J:338226 Zhang Y, et al., Effects of transforming growth factor-beta1 on odontoblastic differentiation in dental papilla cells is determined by IPO7 expression level. Biochem Biophys Res Commun. 2021 Mar 19;545:105-111 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 09/17/2024 MGI 6.24 |
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