Sequence Detail

ID/Version

Q7TSI1 Q8CHU5 Q3U3L2 (UniProt | EBI)

Last sequence update: 2003-10-01
Last annotation update: 2024-05-29

Sequence description from provider

RecName: Full=Pleckstrin homology domain-containing family M member 1 {ECO:0000305}; Short=PH domain-containing family M member 1;

Provider

SWISS-PROT

Sequence

Polypeptide 1074 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Plekhm1	pleckstrin homology domain containing, family M (with RUN domain) member 1	26	96	3	200

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:180994 Ye S, et al., LIS1 regulates osteoclast formation and function through its interactions with dynein/dynactin and Plekhm1. PLoS One. 2011;6(11):e27285
J:219629 McEwan DG, et al., PLEKHM1 regulates autophagosome-lysosome fusion through HOPS complex and LC3/GABARAP proteins. Mol Cell. 2015 Jan 8;57(1):39-54
J:236517 Fujiwara T, et al., PLEKHM1/DEF8/RAB7 complex regulates lysosome positioning and bone homeostasis. JCI Insight. 2016 Oct 20;1(17):e86330
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89