Sequence Detail

ID/Version

Q8BHB0 Q8BUT6 (UniProt | EBI)

Last sequence update: 2003-03-01
Last annotation update: 2024-05-29

Sequence description from provider

RecName: Full=Nucleotide-binding oligomerization domain-containing protein 1 {ECO:0000303|PubMed:16211083}; Short=mNod1 {ECO:0000303|PubMed:16211083};

Provider

SWISS-PROT

Sequence

Polypeptide 953 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Nod1	nucleotide-binding oligomerization domain containing 1	81	100	3	45

Sequence references in MGI

J:85240 Chamaillard M, et al., An essential role for NOD1 in host recognition of bacterial peptidoglycan containing diaminopimelic acid. Nat Immunol. 2003 Jul;4(7):702-7
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:103846 Magalhaes JG, et al., Murine Nod1 but not its human orthologue mediates innate immune detection of tracheal cytotoxin. EMBO Rep. 2005 Dec;6(12):1201-7
J:157879 Travassos LH, et al., Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry. Nat Immunol. 2010 Jan;11(1):55-62
J:186805 Schertzer JD, et al., NOD1 activators link innate immunity to insulin resistance. Diabetes. 2011 Sep;60(9):2206-15
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:335612 Keestra-Gounder AM, et al., NOD1 and NOD2 signalling links ER stress with inflammation. Nature. 2016 Apr 21;532(7599):394-7
J:343818 Zhang Q, et al., Intestinal lysozyme liberates Nod1 ligands from microbes to direct insulin trafficking in pancreatic beta cells. Cell Res. 2019 Jul;29(7):516-532