Sequence Detail

ID/Version

Q8C8R3 Q3TM62 Q8CCV0 Q6PCN2 Q80ZZ7 Q3V2X0 Q8BNC1 Q8C445 (UniProt | EBI)

Last sequence update: 2009-02-10
Last annotation update: 2024-05-29

Sequence description from provider

RecName: Full=Ankyrin-2 {ECO:0000250|UniProtKB:Q01484}; Short=ANK-2;AltName: Full=Ankyrin-B {ECO:0000303|PubMed:19007774, ECO:0000303|PubMed:21745462};AltName: Full=Brain ankyrin {ECO:0000250|UniProtKB:Q01484, ECO:0000312|EMBL:AAH59251.1};

Provider

SWISS-PROT

Sequence

Polypeptide 3898 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Ank2	ankyrin 2, brain	115	105	4	48

Sequence references in MGI

J:81699 Mohler PJ, et al., Ankyrin-B mutation causes type 4 long-QT cardiac arrhythmia and sudden cardiac death. Nature. 2003 Feb 6;421(6923):634-9
J:93347 Mohler PJ, et al., Ankyrin-B targets beta2-spectrin to an intracellular compartment in neonatal cardiomyocytes. J Biol Chem. 2004 Oct 17;279(38):40185-93
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:130060 Mohler PJ, et al., Ankyrin-B syndrome: enhanced cardiac function balanced by risk of cardiac death and premature senescence. PLoS One. 2007;2(10):e1051
J:145566 Kizhatil K, et al., Ankyrin-B is required for coordinated expression of beta-2-spectrin, the Na/K-ATPase and the Na/Ca exchanger in the inner segment of rod photoreceptors. Exp Eye Res. 2009 Jan;88(1):57-64
J:150222 Ayalon G, et al., An ankyrin-based mechanism for functional organization of dystrophin and dystroglycan. Cell. 2008 Dec 26;135(7):1189-200
J:175548 Maddala R, et al., Periaxin is required for hexagonal geometry and membrane organization of mature lens fibers. Dev Biol. 2011 Sep 1;357(1):179-90
J:238624 Qu F, et al., Ankyrin-B is a PI3P effector that promotes polarized alpha5beta1-integrin recycling via recruiting RabGAP1L to early endosomes. Elife. 2016 Oct 08;5:e20417
J:263376 Trinidad JC, et al., Comprehensive identification of phosphorylation sites in postsynaptic density preparations. Mol Cell Proteomics. 2006 May;5(5):914-22
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89