Sequence Detail

ID/Version

Q8CBD1 Q8C3Y8 Q9Z2K2 Q3U166 (UniProt | EBI)

Last sequence update: 2003-03-01
Last annotation update: 2024-05-29

Sequence description from provider

RecName: Full=Nuclear receptor-interacting protein 1;AltName: Full=Nuclear factor RIP140;AltName: Full=Receptor-interacting protein 140;

Provider

SWISS-PROT

Sequence

Polypeptide 1161 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Nrip1	nuclear receptor interacting protein 1	52	111	4	123

Sequence references in MGI

J:50521 Lee CH, et al., Cloning and characterization of mouse RIP140, a corepressor for nuclear orphan receptor TR2. Mol Cell Biol. 1998 Nov;18(11):6745-55
J:74971 White R, et al., The nuclear receptor co-repressor nrip1 (RIP140) is essential for female fertility. Nat Med. 2000 Dec;6(12):1368-74
J:90688 Leonardsson G, et al., Nuclear receptor corepressor RIP140 regulates fat accumulation. Proc Natl Acad Sci U S A. 2004 Jun 1;101(22):8437-42
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:113776 Lee CH, et al., Characterization of receptor-interacting protein 140 in retinoid receptor activities. J Biol Chem. 1999 Oct 29;274(44):31320-6
J:113911 Wei LN, et al., Receptor-interacting protein 140 directly recruits histone deacetylases for gene silencing. J Biol Chem. 2000 Dec 29;275(52):40782-7
J:114064 Wei LN, et al., Ligand-dependent formation of retinoid receptors, receptor-interacting protein 140 (RIP140), and histone deacetylase complex is mediated by a novel receptor-interacting motif of RIP140. J Biol Chem. 2001 May 11;276(19):16107-12
J:114719 Huq MD, et al., Post-translational modification of nuclear co-repressor receptor-interacting protein 140 by acetylation. Mol Cell Proteomics. 2005 Jul;4(7):975-83
J:114726 Tullet JM, et al., Multiple signaling defects in the absence of RIP140 impair both cumulus expansion and follicle rupture. Endocrinology. 2005 Sep;146(9):4127-37
J:175152 Gupta P, et al., Retinoic acid-stimulated sequential phosphorylation, PML recruitment, and SUMOylation of nuclear receptor TR2 to suppress Oct4 expression. Proc Natl Acad Sci U S A. 2008 Aug 12;105(32):11424-9
J:213898 Poliandri AH, et al., Modulation of clock gene expression by the transcriptional coregulator receptor interacting protein 140 (RIP140). J Biol Rhythms. 2011 Jun;26(3):187-99
J:245382 Park SW, et al., SUMOylation of Tr2 orphan receptor involves Pml and fine-tunes Oct4 expression in stem cells. Nat Struct Mol Biol. 2007 Jan;14(1):68-75
J:254654 Vivante A, et al., A Dominant Mutation in Nuclear Receptor Interacting Protein 1 Causes Urinary Tract Malformations via Dysregulation of Retinoic Acid Signaling. J Am Soc Nephrol. 2017 Aug;28(8):2364-2376