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Sequence Detail
ID/Version
Q8CIM5 Q99MX9 (UniProt | EBI) Last sequence update: 2003-03-01
Last annotation update: 2024-01-24
Sequence
description
from provider
RecName: Full=G-protein coupled receptor 84;
Provider SWISS-PROT
Sequence
Polypeptide 396 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Gpr84 G protein-coupled receptor 84 5 97 3 12
Sequence references in MGI J:68335 Wittenberger T, et al., An expressed sequence tag (EST) data mining strategy succeeding in the discovery of new G-protein coupled receptors. J Mol Biol. 2001 Mar 30;307(3):799-813
J:117395 Wang J, et al., Medium-chain fatty acids as ligands for orphan G protein-coupled receptor GPR84. J Biol Chem. 2006 Nov 10;281(45):34457-64
J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:264659 Recio C, et al., Activation of the Immune-Metabolic Receptor GPR84 Enhances Inflammation and Phagocytosis in Macrophages. Front Immunol. 2018;9:1419
J:327304 Zhang Q, et al., GPR84 signaling promotes intestinal mucosal inflammation via enhancing NLRP3 inflammasome activation in macrophages. Acta Pharmacol Sin. 2022 Aug;43(8):2042-2054

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
06/12/2024
MGI 6.13
The Jackson Laboratory