Sequence Detail

ID/Version

Q8R2Y0 Q9DCD4 Q3TGD2 (UniProt | EBI)

Last sequence update: 2002-06-01
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Monoacylglycerol lipase ABHD6 {ECO:0000305}; EC=3.1.1.23 {ECO:0000269|PubMed:18096503, ECO:0000269|PubMed:24095738};AltName: Full=2-arachidonoylglycerol hydrolase {ECO:0000303|PubMed:18096503};AltName: Full=Abhydrolase domain-contain

Provider

SWISS-PROT

Sequence

Polypeptide 336 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Abhd6	abhydrolase domain containing 6	23	97	4	21

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:163762 Marrs WR, et al., The serine hydrolase ABHD6 controls the accumulation and efficacy of 2-AG at cannabinoid receptors. Nat Neurosci. 2010 Aug;13(8):951-7
J:203779 Thomas G, et al., The serine hydrolase ABHD6 Is a critical regulator of the metabolic syndrome. Cell Rep. 2013 Oct 31;5(2):508-20
J:217994 Blankman JL, et al., A comprehensive profile of brain enzymes that hydrolyze the endocannabinoid 2-arachidonoylglycerol. Chem Biol. 2007 Dec;14(12):1347-56
J:227417 Pribasnig MA, et al., alpha/beta Hydrolase Domain-containing 6 (ABHD6) Degrades the Late Endosomal/Lysosomal Lipid Bis(monoacylglycero)phosphate. J Biol Chem. 2015 Dec 11;290(50):29869-81
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89