ID/Version |
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Sequence description from provider |
RecName: Full=Prolow-density lipoprotein receptor-related protein 1 {ECO:0000305}; Short=LRP-1;AltName: Full=Alpha-2-macroglobulin receptor; Short=A2MR;AltName: CD_antigen=CD91;Contains: RecName: Full=Low-density lipoprotein receptor-rela | ||||||||||||||
Provider | SWISS-PROT | ||||||||||||||
Sequence |
Polypeptide
4545
aa
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Source | |||||||||||||||
Annotated genes and markers |
Follow the symbol links to get more information on the GO terms,
expression assays, orthologs, phenotypic alleles, and other information
for the genes or markers below.
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Sequence references in MGI |
J:4760
Van Leuven F, et al., Molecular cloning and sequencing of the murine alpha-2-macroglobulin receptor cDNA. Biochim Biophys Acta. 1993 Apr 29;1173(1):71-4
J:30077 Herz J, et al., LDL receptor-related protein internalizes and degrades uPA-PAI-1 complexes and is essential for embryo implantation [published erratum appears in Cell 1993 May 7;73(3):428]. Cell. 1992 Oct 30;71(3):411-21 J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54 J:188910 Morris SM, et al., Disabled-2 colocalizes with the LDLR in clathrin-coated pits and interacts with AP-2. Traffic. 2001 Feb;2(2):111-23 J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30 J:273590 Muramatsu H, et al., LDL receptor-related protein as a component of the midkine receptor. Biochem Biophys Res Commun. 2000 Apr 21;270(3):936-41 J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89 J:292724 Rauch JN, et al., LRP1 is a master regulator of tau uptake and spread. Nature. 2020 Apr;580(7803):381-385 J:344260 Yan W, et al., Heterozygous LRP1 deficiency causes developmental dysplasia of the hip by impairing triradiate chondrocytes differentiation due to inhibition of autophagy. Proc Natl Acad Sci U S A. 2022 Sep 13;119(37):e2203557119 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 09/17/2024 MGI 6.24 |
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