Sequence Detail

ID/Version

Q99JY1 Q91ZW0 (UniProt | EBI)

Last sequence update: 2001-06-01
Last annotation update: 2024-05-29

Sequence description from provider

RecName: Full=Toll/interleukin-1 receptor domain-containing adapter protein; Short=TIR domain-containing adapter protein;AltName: Full=Adaptor protein Wyatt;AltName: Full=MyD88 adapter-like protein;

Provider

SWISS-PROT

Sequence

Polypeptide 241 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Tirap	toll-interleukin 1 receptor (TIR) domain-containing adaptor protein	93	97	3	10

Sequence references in MGI

J:72250 Horng T, et al., TIRAP: an adapter molecule in the Toll signaling pathway. Nat Immunol. 2001 Sep;2(9):835-41
J:180126 Troutman TD, et al., Role for B-cell adapter for PI3K (BCAP) as a signaling adapter linking Toll-like receptors (TLRs) to serine/threonine kinases PI3K/Akt. Proc Natl Acad Sci U S A. 2012 Jan 3;109(1):273-8