Sequence Detail

ID/Version

Q99K10 (UniProt | EBI)

Last sequence update: 2003-05-23
Last annotation update: 2024-05-29

Sequence description from provider

RecName: Full=Neuroligin-1;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 843 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Nlgn1	neuroligin 1	166	101	3	12

Sequence references in MGI

J:83413 Okazaki N, et al., Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. DNA Res. 2003 Feb 28;10(1):35-48
J:113647 Varoqueaux F, et al., Neuroligins determine synapse maturation and function. Neuron. 2006 Sep 21;51(6):741-54
J:116404 Scheiffele P, et al., Neuroligin expressed in nonneuronal cells triggers presynaptic development in contacting axons. Cell. 2000 Jun 9;101(6):657-69
J:127247 Budreck EC, et al., Neuroligin-3 is a neuronal adhesion protein at GABAergic and glutamatergic synapses. Eur J Neurosci. 2007 Oct;26(7):1738-48
J:134615 Bolliger MF, et al., Unusually rapid evolution of Neuroligin-4 in mice. Proc Natl Acad Sci U S A. 2008 Apr 29;105(17):6421-6
J:155550 Bottos A, et al., The synaptic proteins neurexins and neuroligins are widely expressed in the vascular system and contribute to its functions. Proc Natl Acad Sci U S A. 2009 Dec 8;106(49):20782-7
J:157848 Blundell J, et al., Neuroligin-1 deletion results in impaired spatial memory and increased repetitive behavior. J Neurosci. 2010 Feb 10;30(6):2115-29
J:175189 Graf ER, et al., Neurexins induce differentiation of GABA and glutamate postsynaptic specializations via neuroligins. Cell. 2004 Dec 29;119(7):1013-26
J:197398 El Helou J, et al., Neuroligin-1 links neuronal activity to sleep-wake regulation. Proc Natl Acad Sci U S A. 2013 Jun 11;110(24):9974-9
J:245291 Chen X, et al., Structural basis for synaptic adhesion mediated by neuroligin-neurexin interactions. Nat Struct Mol Biol. 2008 Jan;15(1):50-6
J:247060 Nakanishi M, et al., Functional significance of rare neuroligin 1 variants found in autism. PLoS Genet. 2017 Aug;13(8):e1006940
J:277096 Zhang P, et al., Heparan Sulfate Organizes Neuronal Synapses through Neurexin Partnerships. Cell. 2018 Sep 6;174(6):1450-1464.e23
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89