Sequence Detail

ID/Version

Q9ER60 A2VDE9 B1ARK0 (UniProt | EBI)

Last sequence update: 2001-03-01
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=Sodium channel protein type 4 subunit alpha;AltName: Full=Sodium channel protein skeletal muscle subunit alpha;AltName: Full=Sodium channel protein type IV subunit alpha;AltName: Full=Voltage-gated sodium channel subunit alpha Nav1.4;

Provider

SWISS-PROT

Sequence

Polypeptide 1841 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Scn4a	sodium channel, voltage-gated, type IV, alpha	23	101	4	10

Sequence references in MGI

J:108205 Zimmer T, et al., Mouse heart Na+ channels: primary structure and function of two isoforms and alternatively spliced variants. Am J Physiol Heart Circ Physiol. 2002 Mar;282(3):H1007-17
J:135831 Hayward LJ, et al., Targeted mutation of mouse skeletal muscle sodium channel produces myotonia and potassium-sensitive weakness. J Clin Invest. 2008 Apr;118(4):1437-49
J:178228 Wu F, et al., A sodium channel knockin mutant (NaV1.4-R669H) mouse model of hypokalemic periodic paralysis. J Clin Invest. 2011 Oct 3;121(10):4082-94