Sequence Detail

ID/Version

Q9ESB3 Q6YKA2 Q99PS6 Q99PS5 Q6YK32 (UniProt | EBI)

Last sequence update: 2011-05-31
Last annotation update: 2024-05-29

Sequence description from provider

RecName: Full=Histidine-rich glycoprotein;AltName: Full=Histidine-proline-rich glycoprotein; Short=HPRG;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 525 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Hrg	histidine-rich glycoprotein	75	96	4	8

Sequence references in MGI

J:71004 Hulett MD, et al., Murine histidine-rich glycoprotein: cloning, characterization and cellular origin. Immunol Cell Biol. 2000 Jun;78(3):280-7
J:93229 Hsu SJ, et al., Identification of Fetuin-B as a member of a cystatin-like gene family on mouse chromosome 16 with tumor suppressor activity. Genome. 2004 Oct;47(5):931-46
J:96478 Simantov R, et al., The antiangiogenic effect of thrombospondin-2 is mediated by CD36 and modulated by histidine-rich glycoprotein. Matrix Biol. 2005 Feb;24(1):27-34
J:134621 Tsuchida-Straeten N, et al., Enhanced blood coagulation and fibrinolysis in mice lacking histidine-rich glycoprotein (HRG). J Thromb Haemost. 2005 May;3(5):865-72
J:169468 Ringvall M, et al., Enhanced platelet activation mediates the accelerated angiogenic switch in mice lacking histidine-rich glycoprotein. PLoS One. 2011;6(1):e14526
J:177146 Rydengard V, et al., Histidine-rich glycoprotein protects from systemic Candida infection. PLoS Pathog. 2008 Aug;4(8):e1000116
J:185672 Tugues S, et al., Genetic deficiency in plasma protein HRG enhances tumor growth and metastasis by exacerbating immune escape and vessel abnormalization. Cancer Res. 2012 Apr 15;72(8):1953-63
J:205242 Thulin A, et al., Activated platelets provide a functional microenvironment for the antiangiogenic fragment of histidine-rich glycoprotein. Mol Cancer Res. 2009 Nov;7(11):1792-802
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89