Sequence Detail

ID/Version

Q9WVR4 Q9WVR5 (UniProt | EBI)

Last sequence update: 1999-11-01
Last annotation update: 2024-05-29

Sequence description from provider

RecName: Full=RNA-binding protein FXR2 {ECO:0000305}; Short=FXR2P {ECO:0000303|PubMed:11438699};

Provider

SWISS-PROT

Sequence

Polypeptide 673 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Fxr2	FMR1 autosomal homolog 2	37	102	3	15

Sequence references in MGI

J:57450 Miyashita A, et al., Five different genes, Eif4a1, Cd68, Supl15h, Sox15 and Fxr2h, are clustered in a 40 kb region of mouse chromosome 11. Gene. 1999 Sep 3;237(1):53-60
J:75389 Bontekoe CJ, et al., Knockout mouse model for Fxr2: a model for mental retardation. Hum Mol Genet. 2002 Mar 1;11(5):487-98
J:88664 Schenck A, et al., A highly conserved protein family interacting with the fragile X mental retardation protein (FMRP) and displaying selective interactions with FMRP-related proteins FXR1P and FXR2P. Proc Natl Acad Sci U S A. 2001 Jul 17;98(15):8844-9
J:112066 Spencer CM, et al., Exaggerated behavioral phenotypes in Fmr1/Fxr2 double knockout mice reveal a functional genetic interaction between Fragile X-related proteins. Hum Mol Genet. 2006 Jun 15;15(12):1984-94
J:174968 Guo W, et al., RNA-binding protein FXR2 regulates adult hippocampal neurogenesis by reducing Noggin expression. Neuron. 2011 Jun 9;70(5):924-38
J:263455 Wang GX, et al., Sub-synaptic, multiplexed analysis of proteins reveals Fragile X related protein 2 is mislocalized in Fmr1 KO synapses. Elife. 2016 Oct 22;5:e20560
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89