ID/Version |
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Sequence description from provider |
RecName: Full=Protein fem-1 homolog A-A {ECO:0000305}; Short=FEM1a-A {ECO:0000305};AltName: Full=FEM1-alpha-A {ECO:0000305};AltName: Full=Prostaglandin E receptor 4-associated protein {ECO:0000303|PubMed:18270204}; | ||||||||||||||
Provider | SWISS-PROT | ||||||||||||||
Sequence |
Polypeptide
654
aa
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Source | |||||||||||||||
Annotated genes and markers |
Follow the symbol links to get more information on the GO terms,
expression assays, orthologs, phenotypic alleles, and other information
for the genes or markers below.
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Sequence references in MGI |
J:51387
Ventura-Holman T, et al., The murine fem1 gene family: homologs of the Caenorhabditis elegans sex- determination protein FEM-1. Genomics. 1998 Dec 1;54(2):221-30
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563 J:135247 Minami M, et al., Prostaglandin E receptor type 4-associated protein interacts directly with NF-kappaB1 and attenuates macrophage activation. J Biol Chem. 2008 Apr 11;283(15):9692-703 J:228893 Nakatsuji M, et al., EP4 Receptor-Associated Protein in Macrophages Ameliorates Colitis and Colitis-Associated Tumorigenesis. PLoS Genet. 2015 Oct;11(10):e1005542 J:244450 Fujikawa R, et al., Deficiency in EP4 Receptor-Associated Protein Ameliorates Abnormal Anxiety-Like Behavior and Brain Inflammation in a Mouse Model of Alzheimer Disease. Am J Pathol. 2017 Aug;187(8):1848-1854 J:253904 Fujikawa R, et al., Behavioral abnormalities and reduced norepinephrine in EP4 receptor-associated protein (EPRAP)-deficient mice. Biochem Biophys Res Commun. 2017 Apr 29;486(2):584-588 J:304242 Fujikawa R, et al., EP4 Receptor-Associated Protein in Microglia Promotes Inflammation in the Brain. Am J Pathol. 2016 Aug;186(8):1982-1988 J:304573 Cambier L, et al., Fem1a is a mitochondrial protein up-regulated upon ischemia-reperfusion injury. FEBS Lett. 2009 May 19;583(10):1625-30 J:319834 Higuchi S, et al., EP4 Receptor-Associated Protein in Macrophages Protects against Bleomycin-Induced Pulmonary Inflammation in Mice. J Immunol. 2016 Dec 1;197(11):4436-4443 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 09/17/2024 MGI 6.24 |
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