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    GO Term Detail
    Term: RNA polymerase II transcription regulatory region sequence-specific DNA binding
    Synonyms: RNA polymerase II regulatory region DNA binding
    Definition: Binding to a specific sequence of DNA that is part of a regulatory region that controls the transcription of a gene or cistron by RNA polymerase II.
    Parent Terms: is-a transcription cis-regulatory region binding
    Comment: To minimize ambiguity in the use of the word "promoter" in GO, we have chosen the phrase "transcription regulatory region" to refer to all of the regulatory regions. Regulatory regions in the DNA which control initiation may include the "core promoter" where the basal transcription machinery binds, the "core promoter proximal region" where regulatory factors other than the basal machinery bind. There are also additional regulatory regions, in both the DNA and the RNA transcript, which regulate elongation or termination of transcription.
    Category: Molecular Function
    ID: GO:0000977
    Other IDs: GO:0001012
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    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    last database update
    03/18/2025
    MGI 6.24
    The Jackson Laboratory