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    GO Term Detail
    Term: RNA polymerase II cis-regulatory region sequence-specific DNA binding
    Synonyms: RNA polymerase II core promoter proximal region sequence-specific DNA binding | RNA polymerase II distal enhancer sequence-specific DNA binding | RNA polymerase II promoter proximal region sequence-specific DNA binding | RNA polymerase II proximal promoter sequence-specific DNA binding | RNA polymerase II upstream activating sequence (UAS) sequence-specific DNA binding
    Definition: Binding to a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in cis relative to the transcription start site (i.e., on the same strand of DNA) of a gene transcribed by RNA polymerase II.
    Parent Terms: is-a cis-regulatory region sequence-specific DNA binding
    is-a RNA polymerase II transcription regulatory region sequence-specific DNA binding
    Comment: Note that the phrase "upstream activating sequence", or UAS is often used in S. cerevisiae literature to refer to cis-regulatory sequences. In bacteria such as E. coli, the phrase "upstream activating sequence", or UAS is usually a synonym for "enhancer".
    Category: Molecular Function
    ID: GO:0000978
    Other IDs: GO:0000980
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    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    03/25/2025
    MGI 6.24     		The Jackson Laboratory