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    GO Term Detail
    Term: DNA-binding transcription repressor activity, RNA polymerase II-specific
    Synonyms: distal enhancer DNA-binding transcription repressor activity, RNA polymerase II-specific | metal ion regulated core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity involved in negative regulation of transcription | metal ion regulated sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription | proximal promoter DNA-binding transcription repressor activity, RNA polymerase II-specific | RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription | RNA polymerase II distal enhancer sequence-specific DNA-binding transcription factor activity involved in negative regulation of transcription | RNA polymerase II transcriptional repressor activity, metal ion regulated core promoter proximal region sequence-specific binding | RNA polymerase II transcriptional repressor activity, metal ion regulated proximal promoter sequence-specific DNA binding | RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription | sequence-specific distal enhancer binding RNA polymerase II transcription factor activity involved in negative regulation of transcription | transcriptional repressor activity, metal ion regulated sequence-specific DNA binding | transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding | transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
    Definition: A DNA-binding transcription factor activity that represses or decreases the transcription of specific gene sets transcribed by RNA polymerase II.
    Parent Terms: is-a DNA-binding transcription factor activity, RNA polymerase II-specific
    is-a DNA-binding transcription repressor activity
    Comment: For usage guidance, see comment in GO:0003700 ; DNA-binding transcription factor activity.
    Category: Molecular Function
    ID: GO:0001227
    Other IDs: GO:0001078, GO:0001206, GO:0001210, GO:0001214
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    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    03/18/2025
    MGI 6.24     		The Jackson Laboratory